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anti-Elk1 antibody :: Rabbit Elk1 (Ab-389) Antibody

Scan QR to view Datasheet Catalog #    MBS003628 anti-Elk1 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Elk1 (Ab-389), Antibody

 Also Known As   

Rabbit Elk1 (Ab-389) Antibody

 Product Gene Name   

anti-Elk1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: X; NC_000023.10 (47494919..47510003, complement). Location: Xp11.2
 OMIM    311040
 3D Structure    ModBase 3D Structure for P19419
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-Elk1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Elk1 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for Elk1. It may not necessarily be applicable to this product.
 NCBI GI #    166362732
 NCBI GeneID    2002
 NCBI Accession #    NP_001107595.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001114123.2 [Other Products]
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 UniProt Primary Accession #    P19419 [Other Products]
 UniProt Secondary Accession #    O75606; O95058; Q969X8; Q9UJM4; B2R7H4 [Other Products]
 UniProt Related Accession #    P19419 [Other Products]
 Molecular Weight    44,888 Da
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 NCBI Official Full Name    ETS domain-containing protein Elk-1 isoform a
 NCBI Official Synonym Full Names    ELK1, member of ETS oncogene family
 NCBI Official Symbol    ELK1 [Similar Products]
 NCBI Protein Information    ETS domain-containing protein Elk-1; ETS-like gene 1; tyrosine kinase (ELK1) oncogene
 UniProt Protein Name    ETS domain-containing protein Elk-1
 Protein Family    ETS domain-containing protein
 UniProt Gene Name    ELK1 [Similar Products]
 UniProt Entry Name    ELK1_HUMAN
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 NCBI Summary for Elk1    This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]
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 UniProt Comments for Elk1    ELK1: a transcription factor of the Ets family and the ternary complex factor (TCF) subfamily. Forms a ternary complex by binding to the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. Mediates gene activity in response to serum and growth factors. Phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C-terminus; phosphorylation at these sites is critical for transcriptional activation by Elk-1. Two alternatively-spliced isoforms have been described.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: Xp11.2

Cellular Component: nucleoplasm; mitochondrion; cell soma; dendrite; nerve terminal; nucleus

Molecular Function: protein binding; double-stranded DNA binding; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; response to light stimulus; nerve growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; MyD88-independent toll-like receptor signaling pathway; stress-activated MAPK cascade; toll-like receptor 3 signaling pathway; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 5 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; cell differentiation; toll-like receptor 4 signaling pathway
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 Research Articles on Elk1    1. The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Elk1 antibodyPathways associated with anti-Elk1 antibody
 Reference Product  PubMed Publications
 MAPK3 antibody  >103 publications with Elk1 and MAPK3
 SRF antibody  >69 publications with Elk1 and SRF
 MAP2K1 antibody  >18 publications with Elk1 and MAP2K1
 GRB2 antibody  >14 publications with Elk1 and GRB2
 MAPK8 antibody  >5 publications with Elk1 and MAPK8
 CREBBP antibody  >3 publications with Elk1 and CREBBP
 KLF4 antibody  >3 publications with Elk1 and KLF4
 BRCA1 antibody  >2 publications with Elk1 and BRCA1
 SNCA antibody  >2 publications with Elk1 and SNCA
 MAPK14 antibody  >2 publications with Elk1 and MAPK14
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 ERK/MAPK Targets Pathway antibodies  ERK/MAPK Targets Pathway Diagram
 Endometrial Cancer Pathway antibodies  Endometrial Cancer Pathway Diagram
 Endometrial Cancer Pathway antibodies  Endometrial Cancer Pathway Diagram
Diseases associated with anti-Elk1 antibodyOrgans/Tissues associated with anti-Elk1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >112 publications with Elk1 and Neoplasms
 Nervous System Diseases Antibodies  >26 publications with Elk1 and Nervous System Diseases
 Adenocarcinoma Antibodies  >23 publications with Elk1 and Adenocarcinoma
 Necrosis Antibodies  >17 publications with Elk1 and Necrosis
 Inflammation Antibodies  >16 publications with Elk1 and Inflammation
 Breast Neoplasms Antibodies  >15 publications with Elk1 and Breast Neoplasms
 Drug Toxicity Antibodies  >13 publications with Elk1 and Drug Toxicity
 Atherosclerosis Antibodies  >11 publications with Elk1 and Atherosclerosis
 Lung Neoplasms Antibodies  >11 publications with Elk1 and Lung Neoplasms
 Prostatic Neoplasms Antibodies  >10 publications with Elk1 and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >96 publications with Elk1 and Brain
 Lung Antibodies  >29 publications with Elk1 and Lung
 Liver Antibodies  >13 publications with Elk1 and Liver
 Testis Antibodies  >5 publications with Elk1 and Testis
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