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anti-EFNB2 antibody :: Ephrin-B2 Antibody

Scan QR to view Datasheet Catalog #    MBS856871
Western Blot (WB)
Unit / Price
0.05 mg  /  $180 +1 FREE 8GB USB
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ephrin-B2 (EFNB2), Antibody

 Also Known As   

Ephrin-B2 (Ab-330) Antibody

 Product Gene Name   

anti-EFNB2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600527
 3D Structure    ModBase 3D Structure for P52799
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 Species Reactivity    Human, Mouse, Rat
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 Specificity    Ephrin-B2 (Ab-330) antibody detects endogenous levels of total Ephrin-B2 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized non-phosphopeptide derived from human Ephrin-B2 around the phosphorylation site of tyrosine 330 (N-I-YP-Y-K).
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 Preparation and Storage    Store at-20 degree C for 1 year
 Other Notes    Small volumes of anti-EFNB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-EFNB2 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-EFNB2 antibody   

Western Blot (WB)

 Application Notes for anti-EFNB2 antibody    WB: 1:500-1:1000
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 Western Blot (WB) of anti-EFNB2 antibody    Western blot analysis of extract from A431 cells untreated or treated with Insulin, using Ephrin-B2 (Ab-330) antibody.
anti-EFNB2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for EFNB2. It may not necessarily be applicable to this product.
 NCBI GI #    4758250
 NCBI GeneID    1948
 NCBI Accession #    NP_004084.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004093.3 [Other Products]
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 UniProt Primary Accession #    P52799 [Other Products]
 UniProt Secondary Accession #    Q5JV56 [Other Products]
 UniProt Related Accession #    P52799 [Other Products]
 Molecular Weight    36,923 Da [Similar Products]
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 NCBI Official Full Name    ephrin-B2
 NCBI Official Synonym Full Names    ephrin B2
 NCBI Official Symbol    EFNB2 [Similar Products]
 NCBI Official Synonym Symbols   
HTKL; EPLG5; Htk-L; LERK5
[Similar Products]
 NCBI Protein Information    ephrin-B2
 UniProt Protein Name    Ephrin-B2
 UniProt Synonym Protein Names   
EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L
 Protein Family    Ephrin
 UniProt Gene Name    EFNB2 [Similar Products]
 UniProt Synonym Gene Names    EPLG5; HTKL; LERK5; LERK-5; HTK-L [Similar Products]
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 NCBI Summary for EFNB2    This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]
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 UniProt Comments for EFNB2    Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
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Product References and Citations for anti-EFNB2 antibody

   Chrencik JE, et al.(2006) J Biol Chem; 281(38):28185-28192. Kertesz N, et al. (2006) Blood; 107(6):2330-2338. Noren NK, et al. (2004) Proc Natl Acad Sci USA; 101(15):5583-5588.
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 Research Articles on EFNB2    1. This is the novel report describing to demonstrate that the Runx2 expression of MSC is synergistically influenced by the hydrogels elasticity and their manner of ephrinB2 immobilized.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EFNB2 antibodyPathways associated with anti-EFNB2 antibody
 Reference Product  PubMed Publications
 EPHB4 antibody  >15 publications with EFNB2 and EPHB4
 EPHB2 antibody  >9 publications with EFNB2 and EPHB2
 EPHB6 antibody  >8 publications with EFNB2 and EPHB6
 EPHB1 antibody  >4 publications with EFNB2 and EPHB1
 EPHA4 antibody  >4 publications with EFNB2 and EPHA4
 EPHA6 antibody  >1 publications with EFNB2 and EPHA6
 EPHB3 antibody  >1 publications with EFNB2 and EPHB3
 SRC antibody  >1 publications with EFNB2 and SRC
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 EPHB Forward Signaling Pathway antibodies  EPHB Forward Signaling Pathway Diagram
 Ephrin B Reverse Signaling Pathway antibodies  Ephrin B Reverse Signaling Pathway Diagram
 EphrinB-EPHB Pathway antibodies  EphrinB-EPHB Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
Diseases associated with anti-EFNB2 antibodyOrgans/Tissues associated with anti-EFNB2 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >16 publications with EFNB2 and Neoplasms
 Nervous System Diseases Antibodies  >8 publications with EFNB2 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >6 publications with EFNB2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >5 publications with EFNB2 and Disease Models, Animal
 Chromosome Aberrations Antibodies  >3 publications with EFNB2 and Chromosome Aberrations
 Neoplasms, Experimental Antibodies  >2 publications with EFNB2 and Neoplasms, Experimental
 Nervous System Malformations Antibodies  >2 publications with EFNB2 and Nervous System Malformations
 Adenocarcinoma Antibodies  >2 publications with EFNB2 and Adenocarcinoma
 Heart Diseases Antibodies  >2 publications with EFNB2 and Heart Diseases
 Infertility, Female Antibodies  >2 publications with EFNB2 and Infertility, Female
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >20 publications with EFNB2 and Vascular
 Blood Antibodies  >18 publications with EFNB2 and Blood
 Bone Antibodies  >9 publications with EFNB2 and Bone
 Embryonic Tissue Antibodies  >9 publications with EFNB2 and Embryonic Tissue
 Brain Antibodies  >9 publications with EFNB2 and Brain
 Eye Antibodies  >7 publications with EFNB2 and Eye
 Heart Antibodies  >5 publications with EFNB2 and Heart
 Liver Antibodies  >4 publications with EFNB2 and Liver
 Thymus Antibodies  >4 publications with EFNB2 and Thymus
 Spleen Antibodies  >4 publications with EFNB2 and Spleen
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