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Rabbit FLIP (CT) Antibody

Scan QR to view Datasheet Catalog #    MBS194089 anti-FLIP (CT) antibody
Unit / Price
0.1 mg  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FLIP (CT), Antibody

 Also Known As   

Anti-FLIP gamma / delta (CT) Antibody

 Product Synonym Names    Anti-FLIP (CT); FLIP g/d (CT)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Host    Rabbit
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 Specificity    Anti-FLIP (CT) [Rabbit antibody to peptide corresponding to aa 191-209 at C-terminus of human FLIP. Does not recongnize FLIPa or FLIPb.]
This antibody recognizes human and mouse FLIP gamma (35 kD) and FLIP delta (25 kD) but not FLIP alpha or FLIP beta .
 Form/Format    100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
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 Antigen    Peptide corresponding to aa 191- 209 at the C-terminus of human FLIP delta /FLIPS form.
 Stabilizer    None
 Preservatives    0.02% sodium azide.
 Dilutions Instructions    Dilute in PBS or medium which is identical to that used in the assay system.
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 Preparation and Storage    This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of anti-FLIP (CT) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FLIP (CT) antibody

   Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the ICE/CED-3 protease family. Caspase-8 (FLICE) and -10 (FLICE2) are two pivotal members of the ICE/CED-3 protease family. FLICE-inhibitory proteins have been identified in viruses and human cells and are designated v-FLIPs and FLIP, respectively. Human FLIP was cloned by several independent laboratories and designated Casper, I-FLICE, FLAME-1, CASH, and CLARP. FLIP contains two death effector domains and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and -10 and potently inhibits apoptosis induced by death receptors CD95, DR3, TRAIL-R, and TNFR1. Four splice variants of FLIP have been identified and designated FLIP alpha , beta , gamma , and delta .
 Product Categories/Family for anti-FLIP (CT) antibody    Apoptosis Antibodies
 Applications Tested/Suitable for anti-FLIP (CT) antibody   

Immunoblot

 Application Notes for anti-FLIP (CT) antibody    Immunoblotting : use a 1:1,000 dilution.
Positive control: Whole cell lysate from HeLa cells, Jurkat cells, THP-1 cells, A431 cells, K562 cells, or NIH3T3 cells.
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NCBI/Uniprot data below describe general gene information for FLIP (CT). It may not necessarily be applicable to this product.
 NCBI GI #    520562
 NCBI Accession #    AAA67717.1 [Other Products]
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 NCBI Official Full Name    FLIP
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 UniProt Comments for FLIP (CT)    Plays a role in the flagellum-specific transport system.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FLIP (CT) antibodyPathways associated with anti-FLIP (CT) antibody
 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with FLIP (CT) and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with anti-FLIP (CT) antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with FLIP (CT) and Bone
 Connective Tissue Antibodies  >4 publications with FLIP (CT) and Connective Tissue
 Heart Antibodies  >3 publications with FLIP (CT) and Heart
 Muscle Antibodies  >3 publications with FLIP (CT) and Muscle
 Brain Antibodies  >3 publications with FLIP (CT) and Brain
 Vascular Antibodies  >2 publications with FLIP (CT) and Vascular
 Embryonic Tissue Antibodies  >2 publications with FLIP (CT) and Embryonic Tissue
 Ear Antibodies  >1 publications with FLIP (CT) and Ear
 Kidney Antibodies  >1 publications with FLIP (CT) and Kidney
 Umbilical Cord Antibodies  >1 publications with FLIP (CT) and Umbilical Cord
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