NP_001180235.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,446 Da
NCBI Official Full Name
fMet-Leu-Phe receptor
NCBI Official Synonym Full Names
formyl peptide receptor 1
NCBI Official Synonym Symbols
NCBI Protein Information
fMet-Leu-Phe receptor
UniProt Protein Name
fMet-Leu-Phe receptor
UniProt Synonym Protein Names
N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
UniProt Synonym Gene Names
NCBI Summary for FPR1
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
UniProt Comments for FPR1
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1712023, PubMed:10514456).
Product References and Citations for anti-FPR1 antibody
Boulay F., Biochem. Biophys. Res. Commun. 168:1103-1109(1990). Boulay F., Biochemistry 29:11123-11133(1990). Murphy P.M., J. Biol. Chem. 266:12560-12567(1991).
Research Articles on FPR1
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Products associated with anti-FPR1 antibody
Pathways associated with anti-FPR1 antibody
Diseases associated with anti-FPR1 antibody
Organs/Tissues associated with anti-FPR1 antibody
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