NP_002023.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ferritin heavy chain
NCBI Official Synonym Full Names
ferritin heavy chain 1
NCBI Official Synonym Symbols
FHC; FTH; HFE5; PLIF; FTHL6; PIG15 [Similar Products]
NCBI Protein Information
ferritin heavy chain
UniProt Protein Name
Ferritin heavy chain
UniProt Synonym Protein Names
Cell proliferation-inducing gene 15 protein
UniProt Synonym Gene Names
NCBI Summary for FTH1
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for FTH1
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney ().
Research Articles on FTH1
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Products associated with anti-FTH1 antibody
Pathways associated with anti-FTH1 antibody
Diseases associated with anti-FTH1 antibody
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