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anti-FosB antibody :: Rabbit anti-Human, mouse FosB (Phospho-Ser27) Antibody

Scan QR to view Datasheet Catalog #    MBS002312 anti-FosB antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FosB (Phospho-Ser27), Antibody

 Also Known As   

Rabbit FosB (Phospho-Ser27) Antibody

 Product Gene Name   

anti-FosB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000019.9 (45971253..45978437). Location: 19q13.32
 OMIM    164772
 3D Structure    ModBase 3D Structure for P53539
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-FosB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FosB antibody   

Immunofluorescence (IF), ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for FosB. It may not necessarily be applicable to this product.
 NCBI GI #    166999783
 NCBI GeneID    2354
 NCBI Accession #    NP_001107643.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001114171.1 [Other Products]
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 UniProt Primary Accession #    P53539 [Other Products]
 UniProt Secondary Accession #    A8K9K5; A8VJE1; E9PHJ3 [Other Products]
 UniProt Related Accession #    P53539 [Other Products]
 Molecular Weight    35,928 Da
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 NCBI Official Full Name    protein fosB isoform 2
 NCBI Official Synonym Full Names    FBJ murine osteosarcoma viral oncogene homolog B
 NCBI Official Symbol    FOSB [Similar Products]
 NCBI Official Synonym Symbols   
AP-1; G0S3; GOS3; GOSB
[Similar Products]
 NCBI Protein Information    protein fosB; activator protein 1; G0/G1 switch regulatory protein 3
 UniProt Protein Name    Protein fosB
 UniProt Synonym Protein Names   
G0/G1 switch regulatory protein 3
 Protein Family    Protein
 UniProt Gene Name    FOSB [Similar Products]
 UniProt Synonym Gene Names    G0S3 [Similar Products]
 UniProt Entry Name    FOSB_HUMAN
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 NCBI Summary for FosB    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FosB    FosB: FosB interacts with Jun proteins enhancing their DNA binding activity. Heterodimer. Belongs to the bZIP family. Fos subfamily.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; double-stranded DNA binding; transcription factor activity; transcription factor binding

Biological Process: response to drug; transcription from RNA polymerase II promoter; response to cAMP; response to mechanical stimulus; response to morphine; female pregnancy; negative regulation of transcription from RNA polymerase II promoter; response to progesterone stimulus; response to corticosterone stimulus; cellular response to hormone stimulus
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 Research Articles on FosB    1. AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FosB antibodyPathways associated with anti-FosB antibody
 Reference Product  PubMed Publications
 JUNB antibody  >196 publications with FosB and JUNB
 JUND antibody  >167 publications with FosB and JUND
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
Diseases associated with anti-FosB antibodyOrgans/Tissues associated with anti-FosB antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >75 publications with FosB and Nervous System Diseases
 Disease Models, Animal Antibodies  >58 publications with FosB and Disease Models, Animal
 Brain Diseases Antibodies  >58 publications with FosB and Brain Diseases
 Drug Toxicity Antibodies  >52 publications with FosB and Drug Toxicity
 Movement Disorders Antibodies  >40 publications with FosB and Movement Disorders
 Poisoning Antibodies  >34 publications with FosB and Poisoning
 Dyskinesia, Drug-Induced Antibodies  >32 publications with FosB and Dyskinesia, Drug-Induced
 Seizures Antibodies  >20 publications with FosB and Seizures
 Epilepsy Antibodies  >19 publications with FosB and Epilepsy
 Cocaine-Related Disorders Antibodies  >17 publications with FosB and Cocaine-Related Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >332 publications with FosB and Brain
 Blood Antibodies  >77 publications with FosB and Blood
 Muscle Antibodies  >38 publications with FosB and Muscle
 Bone Antibodies  >34 publications with FosB and Bone
 Liver Antibodies  >21 publications with FosB and Liver
 Heart Antibodies  >20 publications with FosB and Heart
 Lung Antibodies  >14 publications with FosB and Lung
 Eye Antibodies  >11 publications with FosB and Eye
 Embryonic Tissue Antibodies  >10 publications with FosB and Embryonic Tissue
 Connective Tissue Antibodies  >9 publications with FosB and Connective Tissue
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