NP_000802.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
51,024 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit alpha-6
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) A receptor, alpha 6
NCBI Protein Information
gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor, alpha 6; GABA subunit A receptor alpha 6; GABA(A) receptor subunit alpha-6
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit alpha-6
UniProt Synonym Protein Names
GABA(A) receptor subunit alpha-6
UniProt Entry Name
GBRA6_HUMAN
NCBI Summary for GABRA6
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for GABRA6
GABRA6: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.
Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, ion channel; Channel, chloride
Chromosomal Location of Human Ortholog: 5q34
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction
Molecular Function: chloride channel activity; GABA-A receptor activity; benzodiazepine receptor activity; extracellular ligand-gated ion channel activity
Biological Process: synaptic transmission; transport; signal transduction; transmembrane transport; gamma-aminobutyric acid signaling pathway
Research Articles on GABRA6
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Pathways associated with anti-GABRA6 antibody
Diseases associated with anti-GABRA6 antibody
Organs/Tissues associated with anti-GABRA6 antibody
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