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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-GSDMA antibody :: GSDMA Antibody

Scan QR to view Datasheet Catalog #    MBS8500376
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GSDMA, Antibody

★Popular Item★
 Also Known As   

GSDMA Antibody

 Product Gene Name   

anti-GSDMA antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611218
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 Other Notes    Small volumes of anti-GSDMA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Testing Data of anti-GSDMA antibody    anti-GSDMA antibody Testing Data image
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 Testing Data #2 of anti-GSDMA antibody    anti-GSDMA antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for GSDMA. It may not necessarily be applicable to this product.
 NCBI GI #    115344386
 NCBI GeneID    284110
 NCBI Accession #    BC109197 [Other Products]
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 UniProt Secondary Accession #    Q32MC5; Q86VE7; Q8N1M6 [Other Products]
 UniProt Related Accession #    Q96QA5 [Other Products]
 Molecular Weight    49,365 Da
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 NCBI Official Full Name    Homo sapiens gasdermin A, mRNA
 NCBI Official Synonym Full Names    gasdermin A
 NCBI Official Symbol    GSDMA [Similar Products]
 NCBI Official Synonym Symbols   
GSDM; FKSG9; GSDM1
[Similar Products]
 NCBI Protein Information    gasdermin-A
 UniProt Protein Name    Gasdermin-A
 UniProt Synonym Protein Names   
Gasdermin-1
 Protein Family    Gasdermin
 UniProt Gene Name    GSDMA [Similar Products]
 UniProt Synonym Gene Names    GSDM; GSDM1 [Similar Products]
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 UniProt Comments for GSDMA    May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).
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 Research Articles on GSDMA    1. modest changes (8-13%) in promoter methylation levels of ZPBP2 and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 and ORMDL3 is mediated by DNA methylation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-GSDMA antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with GSDMA and Neoplasms
 Inflammation Antibodies  >2 publications with GSDMA and Inflammation
 Neoplasm Metastasis Antibodies  >1 publications with GSDMA and Neoplasm Metastasis
 Necrosis Antibodies  >1 publications with GSDMA and Necrosis
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