NP_000168.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
gelsolin isoform a
NCBI Official Synonym Full Names
gelsolin
NCBI Official Synonym Symbols
NCBI Protein Information
gelsolin
UniProt Protein Name
Gelsolin
UniProt Synonym Protein Names
AGEL; Actin-depolymerizing factor; ADF; Brevin
UniProt Synonym Gene Names
NCBI Summary for GSN
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for GSN
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
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Products associated with anti-GSN antibody
Pathways associated with anti-GSN antibody
Diseases associated with anti-GSN antibody
Organs/Tissues associated with anti-GSN antibody
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