Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow GCG  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • OR5AP2 Antibody
 • LPHN1 Antibody
 • FXR2 Antibody
 • Cartilage Glycoprotein 39-Ykl40 ELISA Kit
 • Hepatocyte Nuclear Factor 6 Beta (HNF6beta) ELISA Kit
 • Kappa Immunoglobulin Light Chain (K-LGLC) ELISA Kit
 • Soluble Endothelial Selectin (SE-SELECTIN) ELISA Kit
 • Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) ELISA Kit
 • Basic Fibroblast Growth Factor 4 (BFGF 4) ELISA Kit
 • Apoptosis Signal Regulating Kinase 1 (ASK1) ELISA Kit
 • A Disintegrin and Metalloprotease 8 (ADAM8) ELISA Kit
 • Granulocyte Specific Antinuclear Antibody (GSANA) ELISA Kit
 • Apotransferrin (APOTF) ELISA Kit
 • E2-Ubiquitin-Conjugating Enzyme (E2-UBCE) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-GCG antibody :: Rabbit Glucagon Antibody

Scan QR to view Datasheet Catalog #    MBS001939 anti-GCG antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glucagon (GCG), Antibody

 Also Known As   

Rabbit Glucagon Antibody

 Product Gene Name   

anti-GCG antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 2; NC_000002.11 (162999379..163008914, complement). Location: 2q36-q37
 OMIM    138030
 3D Structure    ModBase 3D Structure for P01275
Section Bar
 Host    Rabbit
 Species Reactivity    Human, mouse, rat
Section Bar
 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
Section Bar
Section Bar
 Other Notes    Small volumes of anti-GCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-GCG antibody   

ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for GCG. It may not necessarily be applicable to this product.
 NCBI GI #    4503945
 NCBI GeneID    2641
 NCBI Accession #    NP_002045.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002054.4 [Other Products]
Section Bar
 UniProt Primary Accession #    P01275 [Other Products]
 UniProt Secondary Accession #    Q53TP6; A6NN65 [Other Products]
 UniProt Related Accession #    P01275 [Other Products]
 Molecular Weight    20,909 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    glucagon preproprotein
 NCBI Official Synonym Full Names    glucagon
 NCBI Official Symbol    GCG [Similar Products]
 NCBI Official Synonym Symbols   
GLP1; GLP2; GRPP
[Similar Products]
 NCBI Protein Information    glucagon; preproglucagon; glucagon-like peptide 1; glucagon-like peptide 2; glicentin-related polypeptide
 UniProt Protein Name    Glucagon
 UniProt Synonym Protein Names   
Incretin hormone
 Protein Family    Glucagon
 UniProt Gene Name    GCG [Similar Products]
 UniProt Synonym Gene Names    GRPP; OXM; OXY; GLP-1; GLP-1(7-37); GLP-1(7-36); GLP-2 [Similar Products]
 UniProt Entry Name    GLUC_HUMAN
Section Bar
 NCBI Summary for GCG    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for GCG    GCG: Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. GLP-1 and GLP-2 are induced in response to nutrient ingestion. Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain. Belongs to the glucagon family.

Protein type: Hormone; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q36-q37

Cellular Component: extracellular space; endoplasmic reticulum lumen; extracellular region; plasma membrane

Molecular Function: identical protein binding; protein binding; hormone activity; glucagon receptor binding; receptor binding

Biological Process: positive regulation of protein binding; positive regulation of histone H3-K4 methylation; signal transduction; positive regulation of peptidyl-serine phosphorylation; G-protein signaling, coupled to cAMP nucleotide second messenger; response to starvation; G-protein coupled receptor protein signaling pathway; cell proliferation; cellular protein metabolic process; positive regulation of protein kinase activity; positive regulation of cAMP biosynthetic process; energy reserve metabolic process; feeding behavior; regulation of insulin secretion; negative regulation of apoptosis
Table BarTOPTable Bar
 Research Articles on GCG    1. we aim to integrate the available data on the metabolic and neuroprotective effects of GLP-1 mimetics in the central nervous system (CNS) with the complex crosstalk between T2D-AD
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-GCG antibodyPathways associated with anti-GCG antibody
 Reference Product  PubMed Publications
 GLP1R antibody  >5 publications with GCG and GLP1R
 GCGR antibody  >4 publications with GCG and GCGR
 GLP2R antibody  >3 publications with GCG and GLP2R
 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glucagon Signaling In Metabolic Regulation Pathway antibodies  Glucagon Signaling In Metabolic Regulation Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Incretin Synthesis, Secretion, And Inactivation Pathway antibodies  Incretin Synthesis, Secretion, And Inactivation Pathway Diagram
Diseases associated with anti-GCG antibodyOrgans/Tissues associated with anti-GCG antibody
 Disease Name  Pubmed Publications
 Muscular Diseases Antibodies  >70 publications with GCG and Muscular Diseases
 Diabetes Mellitus Antibodies  >30 publications with GCG and Diabetes Mellitus
 Vascular Diseases Antibodies  >15 publications with GCG and Vascular Diseases
 Kidney Diseases Antibodies  >11 publications with GCG and Kidney Diseases
 Obesity Antibodies  >11 publications with GCG and Obesity
 Insulin Resistance Antibodies  >10 publications with GCG and Insulin Resistance
 Hyperglycemia Antibodies  >8 publications with GCG and Hyperglycemia
 Heart Diseases Antibodies  >8 publications with GCG and Heart Diseases
 Liver Diseases Antibodies  >7 publications with GCG and Liver Diseases
 Drug Toxicity Antibodies  >7 publications with GCG and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >26 publications with GCG and Pancreas
 Intestine Antibodies  >13 publications with GCG and Intestine
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions