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anti-GYS1 antibody :: Rabbit anti-Human, mouse Glycogen Synthase (Phospho-Ser641) Antibody

Scan QR to view Datasheet Catalog #    MBS003569 anti-GYS1 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glycogen Synthase (Phospho-Ser641) (GYS1), Antibody

 Also Known As   

Rabbit Glycogen Synthase (Phospho-Ser641) Antibody

 Product Gene Name   

anti-GYS1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000019.9 (49471382..49496610, complement). Location: 19q13.3
 OMIM    138570
 3D Structure    ModBase 3D Structure for P13807
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-GYS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-GYS1 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for GYS1. It may not necessarily be applicable to this product.
 NCBI GI #    239049591
 NCBI GeneID    2997
 NCBI Accession #    NP_001155059.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001161587.1 [Other Products]
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 UniProt Primary Accession #    P13807 [Other Products]
 UniProt Secondary Accession #    Q9BTT9 [Other Products]
 UniProt Related Accession #    P13807 [Other Products]
 Molecular Weight    83,786 Da [Similar Products]
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 NCBI Official Full Name    glycogen
 NCBI Official Synonym Full Names    glycogen synthase 1 (muscle)
 NCBI Official Symbol    GYS1 [Similar Products]
 NCBI Official Synonym Symbols   
GSY; GYS
[Similar Products]
 NCBI Protein Information    glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle
 UniProt Protein Name    Glycogen [starch] synthase, muscle
 Protein Family    Glycogen [starch] synthase
 UniProt Gene Name    GYS1 [Similar Products]
 UniProt Synonym Gene Names    GYS [Similar Products]
 UniProt Entry Name    GYS1_HUMAN
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 NCBI Summary for GYS1    The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
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 UniProt Comments for GYS1    GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation.

Protein type: Carbohydrate Metabolism - starch and sucrose; Transferase; EC 2.4.1.11

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: membrane; cytoplasm; inclusion body; cytosol

Molecular Function: protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding

Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis

Disease: Glycogen Storage Disease 0, Muscle
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 Research Articles on GYS1    1. Data suggest that although COOH-terminal dephosphorylation is likely necessary for GS activation, protein kinase Akt-2- (Akt2)-dependent NH2-terminal dephosphorylation is site for "fine-tuning" insulin-mediated GS activation in skeletal muscle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GYS1 antibodyPathways associated with anti-GYS1 antibody
 Reference Product  PubMed Publications
 GSK3B antibody  >1 publications with GYS1 and GSK3B
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
 Glycogen Metabolism Pathway antibodies  Glycogen Metabolism Pathway Diagram
 Glycogen Synthesis Pathway antibodies  Glycogen Synthesis Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin-mediated Glucose Transport Pathway antibodies  Insulin-mediated Glucose Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
Diseases associated with anti-GYS1 antibodyOrgans/Tissues associated with anti-GYS1 antibody
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >11 publications with GYS1 and Insulin Resistance
 Glycogen Storage Disease 0, Muscle Antibodies  >7 publications with GYS1 and Glycogen Storage Disease 0, Muscle
 Cardiovascular Diseases Antibodies  >5 publications with GYS1 and Cardiovascular Diseases
 Inflammation Antibodies  >3 publications with GYS1 and Inflammation
 Hypertension Antibodies  >3 publications with GYS1 and Hypertension
 Neoplasms Antibodies  >2 publications with GYS1 and Neoplasms
 Edema Antibodies  >2 publications with GYS1 and Edema
 Brain Diseases Antibodies  >2 publications with GYS1 and Brain Diseases
 Growth Disorders Antibodies  >2 publications with GYS1 and Growth Disorders
 Heart Diseases Antibodies  >2 publications with GYS1 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >46 publications with GYS1 and Muscle
 Blood Antibodies  >18 publications with GYS1 and Blood
 Liver Antibodies  >11 publications with GYS1 and Liver
 Heart Antibodies  >7 publications with GYS1 and Heart
 Kidney Antibodies  >2 publications with GYS1 and Kidney
 Connective Tissue Antibodies  >2 publications with GYS1 and Connective Tissue
 Brain Antibodies  >2 publications with GYS1 and Brain
 Intestine Antibodies  >1 publications with GYS1 and Intestine
 Embryonic Tissue Antibodies  >1 publications with GYS1 and Embryonic Tissue
 Vascular Antibodies  >1 publications with GYS1 and Vascular
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