NP_001317119.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
high mobility group protein HMGI-C isoform 3
NCBI Official Synonym Full Names
high mobility group AT-hook 2
NCBI Official Synonym Symbols
BABL; LIPO; HMGIC; HMGI-C; STQTL9 [Similar Products]
NCBI Protein Information
high mobility group protein HMGI-C
UniProt Protein Name
High mobility group protein HMGI-C
UniProt Synonym Protein Names
High mobility group AT-hook protein 2
UniProt Synonym Gene Names
NCBI Summary for HMGA2
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for HMGA2
Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation ().
Research Articles on HMGA2
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Products associated with anti-HMGA2 antibody
Pathways associated with anti-HMGA2 antibody
Diseases associated with anti-HMGA2 antibody
Organs/Tissues associated with anti-HMGA2 antibody
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