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anti-IL13RA2 antibody :: Rabbit anti-Human IL13RA2 Antibody

Scan QR to view Datasheet Catalog #    MBS003282 anti-IL13RA2 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL13RA2, Antibody

 Also Known As   

Rabbit IL13RA2 Antibody

 Product Gene Name   

anti-IL13RA2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: X; NC_000023.10 (114238538..114252207, complement). Location: Xq13.1-q28
 OMIM    300130
 3D Structure    ModBase 3D Structure for Q14627
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 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-IL13RA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL13RA2 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for IL13RA2. It may not necessarily be applicable to this product.
 NCBI GI #    10834992
 NCBI GeneID    3598
 NCBI Accession #    NP_000631.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000640.2 [Other Products]
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 UniProt Primary Accession #    Q14627 [Other Products]
 UniProt Secondary Accession #    O00667; A8K7E2 [Other Products]
 UniProt Related Accession #    Q14627 [Other Products]
 Molecular Weight    44,176 Da
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 NCBI Official Full Name    interleukin-13 receptor subunit alpha-2
 NCBI Official Synonym Full Names    interleukin 13 receptor, alpha 2
 NCBI Official Symbol    IL13RA2 [Similar Products]
 NCBI Official Synonym Symbols   
CT19; IL-13R; IL13BP; CD213A2
[Similar Products]
 NCBI Protein Information    interleukin-13 receptor subunit alpha-2; IL-13RA2; IL-13R-alpha-2; IL-13R subunit alpha-2; cancer/testis antigen 19; IL-13 receptor subunit alpha-2; interleukin 13 binding protein; interleukin-13-binding protein; interleukin 13 receptor alpha 2 chain
 UniProt Protein Name    Interleukin-13 receptor subunit alpha-2
 UniProt Synonym Protein Names   
Interleukin-13-binding protein
 Protein Family    Interleukin-13 receptor
 UniProt Gene Name    IL13RA2 [Similar Products]
 UniProt Synonym Gene Names    IL13R; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2 [Similar Products]
 UniProt Entry Name    I13R2_HUMAN
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 NCBI Summary for IL13RA2    The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL13RA2    IL13RA2: a type I membrane protein that binds with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). Lacks a cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. A member of the Cancer-Testis Antigen (CTA) superfamily. CTAs may play roles in embryonal development and tumor transformation or aspects of tumor progression. CTAs were once thought to be silenced in most normal adult tissues, with limited expression in fetal, placental, testis, and ovarian cells. These proteins are now known to be aberrantly expressed in various cancers and many are capable of eliciting humoral and cellular immune responses. The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation. Often overexpressed in brain tumors. A potential vaccine targets for immunotherapy of glioma. Note: This description may include information from RefSeq and UniProtKB

Protein type: Membrane protein, integral; Receptor, cytokine; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: Xq23

Cellular Component: extracellular space; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; signal transducer activity

Biological Process: cytokine and chemokine mediated signaling pathway; signal transduction
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 Research Articles on IL13RA2    1. high expression of IL-13Ralpha2 was associated with later stages of disease progression and poor outcome in patients with colorectal cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL13RA2 antibodyPathways associated with anti-IL13RA2 antibody
 Reference Product  PubMed Publications
 IL13 antibody  >11 publications with IL13RA2 and IL13
 IL4 antibody  >3 publications with IL13RA2 and IL4
 Products by Pathway  Pathway Diagram
 IL4-mediated Signaling Events Pathway antibodies  IL4-mediated Signaling Events Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with anti-IL13RA2 antibodyOrgans/Tissues associated with anti-IL13RA2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >6 publications with IL13RA2 and Inflammation
 Neoplasms Antibodies  >4 publications with IL13RA2 and Neoplasms
 Fibrosis Antibodies  >3 publications with IL13RA2 and Fibrosis
 Brain Diseases Antibodies  >3 publications with IL13RA2 and Brain Diseases
 Drug Toxicity Antibodies  >2 publications with IL13RA2 and Drug Toxicity
 Skin Diseases Antibodies  >2 publications with IL13RA2 and Skin Diseases
 Carcinoma Antibodies  >2 publications with IL13RA2 and Carcinoma
 Necrosis Antibodies  >2 publications with IL13RA2 and Necrosis
 Uterine Cervical Neoplasms Antibodies  >1 publications with IL13RA2 and Uterine Cervical Neoplasms
 Liver Diseases Antibodies  >1 publications with IL13RA2 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with IL13RA2 and Lung
 Brain Antibodies  >3 publications with IL13RA2 and Brain
 Prostate Antibodies  >1 publications with IL13RA2 and Prostate
 Pancreas Antibodies  >1 publications with IL13RA2 and Pancreas
 Connective Tissue Antibodies  >1 publications with IL13RA2 and Connective Tissue
 Adrenal Gland Antibodies  >1 publications with IL13RA2 and Adrenal Gland
 Eye Antibodies  >1 publications with IL13RA2 and Eye
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