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anti-IL-2r antibody :: Mouse Interleukin-2 Antibody

Scan QR to view Datasheet Catalog #    MBS140005 anti-IL-2r antibody
Unit / Price
0.5 mg  /  $230 +1 FREE 8GB USB
1 mg  /  $350 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-2 (IL-2r), Antibody

 Also Known As   

Mouse Anti Human Interleukin-2 receptor

 Product Synonym Names    IL 2r Antibody; Interleukin-2 Receptor (CD25), Mouse Anti-Human; CD25; IL2R; TCGFR; IL-2RA; sIL-2RA; TAC antigen; sIL-2R; IDDM10; p55 TypeMouse Anti Human Monoclonal
 Product Gene Name   

anti-IL-2r antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Isotype    IgG2a
 Clone Number    YNRhIL2R
 Host    Mouse
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 Purity/Purification    Ion Exchange.
 Concentration    1mg/ml in PBS (after reconstitution). (lot specific)
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 Reconstitution    Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
 Immunogen    Con A-activated human T cells.
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 Preparation and Storage    In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
 Other Notes    Small volumes of anti-IL-2r antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-IL-2r antibody

   Introduction: IL2-Ra is one of the three constituent subunits of the IL2 receptor. IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas.
 Product Categories/Family for anti-IL-2r antibody    ANTI-HUMAN CYTOKINES; Monoclonal Antibodies; Anti Human Cytokine
 Applications Tested/Suitable for anti-IL-2r antibody   

Flow Cytometry (FC/FACS)

 Application Notes for anti-IL-2r antibody    1:50 dilution will block 70-80% of CTLL proliferative response to 50 units of r.human IL-2 and will stain 70% of PHA-activated human T cells (by FACS) 10 ul will stain 106 IL-2R positive cells for FACS analysis or sorting.
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NCBI/Uniprot data below describe general gene information for IL-2r. It may not necessarily be applicable to this product.
 NCBI GI #    554168
 NCBI Accession #    AAA39288.1 [Other Products]
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 UniProt Secondary Accession #    Q61731 [Other Products]
 Molecular Weight    30,723 Da
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 NCBI Official Full Name    interleukin 2 receptor, partial
 UniProt Protein Name    Interleukin-2 receptor subunit alpha
 UniProt Synonym Protein Names   
p55; CD_antigen: CD25
 Protein Family    Interleukin
 UniProt Gene Name    Il2ra [Similar Products]
 UniProt Synonym Gene Names    Il2r; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA [Similar Products]
 UniProt Entry Name    IL2RA_MOUSE
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 UniProt Comments for IL-2r    IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Protein type: Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane

Molecular Function: protein binding; interleukin-2 receptor activity; drug binding; interleukin-2 binding

Biological Process: Notch signaling pathway; regulation of T cell homeostatic proliferation; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; negative regulation of lymphocyte proliferation; negative regulation of T cell proliferation; inflammatory response to antigenic stimulus; positive regulation of T cell differentiation; negative regulation of inflammatory response; immune response; positive regulation of T cell proliferation; T cell homeostasis; activated T cell apoptosis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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