NP_004974.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,020 Da
NCBI Official Full Name
G protein-activated inward rectifier potassium channel 3
NCBI Official Synonym Full Names
potassium inwardly-rectifying channel, subfamily J, member 9
NCBI Protein Information
G protein-activated inward rectifier potassium channel 3; GIRK-3; inward rectifier K(+) channel Kir3.3; inwardly rectifier K+ channel KIR3.3; G protein-coupled inward rectifier potassium channel; potassium channel, inwardly rectifying subfamily J member 9
UniProt Protein Name
G protein-activated inward rectifier potassium channel 3
UniProt Synonym Protein Names
Inward rectifier K(+) channel Kir3.3; Potassium channel, inwardly rectifying subfamily J member 9
UniProt Synonym Gene Names
UniProt Entry Name
IRK9_HUMAN
NCBI Summary for KCNJ9
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]
UniProt Comments for KCNJ9
GIRK3: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily.
Protein type: Membrane protein, multi-pass; Channel, potassium; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q23.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: protein binding; G-protein activated inward rectifier potassium channel activity; PDZ domain binding
Biological Process: synaptic transmission; potassium ion import
Research Articles on KCNJ9
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Products associated with anti-KCNJ9 antibody
Pathways associated with anti-KCNJ9 antibody
Diseases associated with anti-KCNJ9 antibody
Organs/Tissues associated with anti-KCNJ9 antibody
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