NP_000215.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
48,058 Da
NCBI Official Full Name
keratin, type I cytoskeletal 18
NCBI Official Synonym Full Names
keratin 18
NCBI Protein Information
keratin, type I cytoskeletal 18
UniProt Protein Name
Keratin, type I cytoskeletal 18
UniProt Synonym Protein Names
Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
UniProt Synonym Gene Names
NCBI Summary for KRT18
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT18
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Product References and Citations for anti-KRT18 antibody
Thomas M. Magin, J. Cell Biol., Mar 1998; 140: 1441. Carlos CaulĂn, J. Cell Biol., Sep 1997; 138: 1379. J Liao, J. Cell Biol., Dec 1995; 131: 1291. Nam-On Ku, J. Clin. Invest., Jan 1997; 99: 19.
Research Articles on KRT18
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Products associated with anti-KRT18 antibody
Pathways associated with anti-KRT18 antibody
Diseases associated with anti-KRT18 antibody
Organs/Tissues associated with anti-KRT18 antibody
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