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anti-LAMA4 antibody :: anti-Human, Mouse LAMA4 Antibody

Scan QR to view Datasheet Catalog #    MBS855508
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LAMA4, Antibody

★Popular Item★
 Also Known As   

LAMA4 Antibody

 Product Synonym Names    Laminin subunit alpha-4 [Precursor]; LAMA4
 Product Gene Name   

anti-LAMA4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600133
 3D Structure    ModBase 3D Structure for Q16363
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 Species Reactivity    Human, Mouse
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 Specificity    LAMA4 antibody detects endogenous levels of total LAMA4 protein.
 Purity/Purification    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human LAMA4.
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 Preparation and Storage    Store at-20 degree C for 1 year.
 Other Notes    Small volumes of anti-LAMA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-LAMA4 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-LAMA4 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-LAMA4 antibody    WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:40000
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 Testing Data of anti-LAMA4 antibody    Peptide-+
anti-LAMA4 antibody Testing Data image
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 Immunohistochemistry (IHC) of anti-LAMA4 antibody    Immunohistochemistry analysis of paraffin-embedded human heart tissue using LAMA4 antibody. Western blot analysis of extracts from COLO cells and 293 cells, using LAMA4 antibody.
anti-LAMA4 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-LAMA4 antibody    Peptide-+ Immunofluorescence analysis of NIH/3T3 cells, using LAMA4 antibody.
anti-LAMA4 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for LAMA4. It may not necessarily be applicable to this product.
 NCBI GI #    380503843
 NCBI GeneID    3910
 NCBI Accession #    NP_001098676.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001105206.2 [Other Products]
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 UniProt Primary Accession #    Q16363 [Other Products]
 UniProt Secondary Accession #    Q14731; Q14735; Q15335; Q4LE44; Q5SZG8; Q9BTB8; Q9UE18; Q9UJN9 [Other Products]
 UniProt Related Accession #    Q16363 [Other Products]
 Molecular Weight    12,819 Da
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 NCBI Official Full Name    laminin subunit alpha-4 isoform 1
 NCBI Official Synonym Full Names    laminin subunit alpha 4
 NCBI Official Symbol    LAMA4 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    laminin subunit alpha-4
 UniProt Protein Name    Laminin subunit alpha-4
 UniProt Synonym Protein Names   
Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alpha
 Protein Family    Laminin
 UniProt Gene Name    LAMA4 [Similar Products]
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 NCBI Summary for LAMA4    Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, however, the exact function of laminin, alpha 4 is not known. Tissue-specific utilization of alternative polyA-signal has been described in literature. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
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 UniProt Comments for LAMA4    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.CautionGene LAMA4 was formerly called LAMA3.
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Product References and Citations for anti-LAMA4 antibody

   Iivanainen A., FEBS Lett. 365:183-188(1995). Richards A.J., Eur. J. Biochem. 238:813-821(1996). Mungall A.J., Nature 425:805-811(2003).
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 Research Articles on LAMA4    1. Disruption of LAMA4, LAMA5, and LAMB2 or the laminin-receptor interaction occurs in neuromuscular diseases including Pierson syndrome and Lambert-Eaton myasthenic syndrome (LEMS). (Review)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LAMA4 antibodyPathways associated with anti-LAMA4 antibody
 Reference Product  PubMed Publications
 GAPDH antibody  >1 publications with LAMA4 and GAPDH
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 FOXM1 Transcription Factor Network Pathway antibodies  FOXM1 Transcription Factor Network Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with anti-LAMA4 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with LAMA4 and Neoplasms
 Inflammation Antibodies  >4 publications with LAMA4 and Inflammation
 Kidney Diseases Antibodies  >3 publications with LAMA4 and Kidney Diseases
 Kidney Neoplasms Antibodies  >2 publications with LAMA4 and Kidney Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with LAMA4 and Carcinoma, Hepatocellular
 Hypertrophy Antibodies  >2 publications with LAMA4 and Hypertrophy
 Lung Neoplasms Antibodies  >2 publications with LAMA4 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with LAMA4 and Neoplasms, Experimental
 Necrosis Antibodies  >2 publications with LAMA4 and Necrosis
 Liver Neoplasms Antibodies  >1 publications with LAMA4 and Liver Neoplasms
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