Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody  rightarrow MLANA rightarrow Monoclonal MLANA  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • BSA Antibody
 • BMP13 Recombinant Protein
 • Alpha-1-Antichymotrypsin (alpha1ACT) ELISA Kit
 • S1 tag Antibody
 • Goat anti Mouse IgM (Fc specific) Secondary Antibody
 • BoTox-A Clone 201F6 (botA) Antibody
 • 1,25-Dihydroxyvitamin D3 (DHVD3) ELISA Kit
 • Adrencocorticotropic Hormone (ACTH) ELISA Kit
 • Glutathione (BSA) conjugate Antigen
 • HIV-M Recombinant Protein
 • UDP-N-acetyl-alpha-D-galact osamine:polypeptide N-acetylgalac... ELISA Kit
 • HSV 1-2 IgG ELISA Kit
 • TLR2 Antibody
 • EAR3 ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

MLANA antibody :: MART-1/Melan-A/MLANA Antibody

Scan QR to view Datasheet Catalog #    MBS439962
Unit / Price
0.02 mg (With BSA & Azide at 0.2mg/ml)  /  $190 +1 FREE 8GB USB
0.1 mg (With BSA & Azide at 0.2mg/ml)  /  $300 +1 FREE 8GB USB
0.1 mg (Without BSA & Azide at 1mg/ml)  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MART-1/Melan-A/MLANA, Antibody

★Popular Item★
 Also Known As   

MART-1/Melan-A/MLANA (Melanoma Marker)

 Product Synonym Names    Antigen LB39-AA; Antigen SK29-AA; Melanoma antigen recognized by T-cells 1; MLAN-A; MLANA
 Product Gene Name   

MLANA antibody

[Similar Products]
 Product Synonym Gene Name    MART-1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for Q16655
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    rMLANA/788
 Host    Mouse
 Species Reactivity    Human, Mouse, Rat, Dog. Others not tested.
Section Bar
 Specificity    This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
 Form/Format    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Section Bar
 Immunogen    Recombinant full-length human MART-1 protein
 Cellular Localization    Cytoplasmic
 Hu-chromosome Location    9p24.1
 Positive Control    SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas
Section Bar
 Preparation and Storage    Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
 Other Notes    Small volumes of MLANA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for MLANA antibody   

Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin

 Application Notes for MLANA antibody    FC/FACS: 0.5-1ug/million cells
IF: 0.5-1ug/ml
WB: 0.5-1.0ug/ml
IHC-F: 0.5-1ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
Section Bar
 Immunohistochemistry (IHC) of MLANA antibody    Formalin-fixed, paraffin-embedded Human Melanoma stained with MART-1 Mouse Recombinant Monoclonal Antibody (rMLANA/788).
MLANA antibody  Immunohistochemistry (IHC) (IHC) image
Section Bar
 SDS-Page of MLANA antibody    SDS-PAGE Analysis of Purified MART-1 Mouse Recombinant Monoclonal Antibody (rMLANA/788).
MLANA antibody  SDS-Page image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for MLANA. It may not necessarily be applicable to this product.
 NCBI GI #    5031913
 NCBI GeneID    2315
 NCBI Accession #    NP_005502.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005511.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q16655 [Other Products]
 UniProt Secondary Accession #    Q6ICU4 [Other Products]
 UniProt Related Accession #    Q16655 [Other Products]
 Molecular Weight    20-22kDa (doublet)
Table BarTOPTable Bar
 NCBI Official Full Name    melanoma antigen recognized by T-cells 1
 NCBI Official Synonym Full Names    melan-A
 NCBI Official Symbol    MLANA [Similar Products]
 NCBI Official Synonym Symbols   
MART1; MART-1
[Similar Products]
 NCBI Protein Information    melanoma antigen recognized by T-cells 1
 UniProt Protein Name    Melanoma antigen recognized by T-cells 1
 UniProt Synonym Protein Names   
Antigen LB39-AA; Antigen SK29-AA; Protein Melan-A
 Protein Family    Melanoma antigen recognized by T-cells
 UniProt Gene Name    MLANA [Similar Products]
 UniProt Synonym Gene Names    MART1; MART-1 [Similar Products]
Section Bar
 UniProt Comments for MLANA    Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Table BarTOPTable Bar
 

Product References and Citations for MLANA antibody

   Chen Y-T, et. al. Proc Natl Acad Sci, USA, 1996, 93:5915-19.
Section Bar
 Research Articles on MLANA    1. Melan-A-stained slides shows definitive invasion.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Diseases associated with MLANA antibody Organs/Tissues associated with MLANA antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >935 publications with MLANA and Neoplasms
 Skin Neoplasms Antibodies  >292 publications with MLANA and Skin Neoplasms
 Carcinoma Antibodies  >77 publications with MLANA and Carcinoma
 Neoplasms, Experimental Antibodies  >63 publications with MLANA and Neoplasms, Experimental
 Necrosis Antibodies  >48 publications with MLANA and Necrosis
 Adenocarcinoma Antibodies  >34 publications with MLANA and Adenocarcinoma
 Nervous System Diseases Antibodies  >32 publications with MLANA and Nervous System Diseases
 Liver Neoplasms Antibodies  >27 publications with MLANA and Liver Neoplasms
 Kidney Diseases Antibodies  >26 publications with MLANA and Kidney Diseases
 Lung Neoplasms Antibodies  >21 publications with MLANA and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >348 publications with MLANA and Skin
 Eye Antibodies  >33 publications with MLANA and Eye
 Kidney Antibodies  >31 publications with MLANA and Kidney
 Brain Antibodies  >21 publications with MLANA and Brain
 Ear Antibodies  >7 publications with MLANA and Ear
 Embryonic Tissue Antibodies  >5 publications with MLANA and Embryonic Tissue
 Mammary Gland Antibodies  >1 publications with MLANA and Mammary Gland
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions