NP_001258867.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
303,100 Da
NCBI Official Full Name
multiple epidermal growth factor-like domains protein 8 isoform 1
NCBI Official Synonym Full Names
multiple EGF-like-domains 8
NCBI Protein Information
multiple epidermal growth factor-like domains protein 8; EGF-like-domain, multiple 4; HBV pre-s2 binding protein 1; EGF-like domain-containing protein 4; epidermal growth factor-like protein 4
UniProt Protein Name
Multiple epidermal growth factor-like domains protein 8
UniProt Synonym Protein Names
Epidermal growth factor-like protein 4
UniProt Synonym Gene Names
C19orf49; EGFL4; KIAA0817; Multiple EGF-like domains protein 8 [Similar Products]
UniProt Entry Name
MEGF8_HUMAN
NCBI Summary for MEGF8
The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
UniProt Comments for MEGF8
MEGF8: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q12
Cellular Component: integral to membrane; nucleus
Molecular Function: protein binding; calcium ion binding; receptor activity
Biological Process: BMP signaling pathway; regulation of gene expression; epiboly involved in gastrulation with mouth forming second; positive regulation of axon extension involved in axon guidance; limb morphogenesis; cell migration involved in gastrulation; embryonic skeletal morphogenesis; embryonic limb morphogenesis
Disease: Carpenter Syndrome 2
Research Articles on MEGF8
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-MEGF8 antibody
Organs/Tissues associated with anti-MEGF8 antibody
|