NP_001129025.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,104 Da
NCBI Official Full Name
MAP kinase-interacting serine/threonine-protein kinase 1 isoform 3
NCBI Official Synonym Full Names
MAP kinase interacting serine/threonine kinase 1
NCBI Official Synonym Symbols
NCBI Protein Information
MAP kinase-interacting serine/threonine-protein kinase 1
UniProt Protein Name
MAP kinase-interacting serine/threonine-protein kinase 1
UniProt Synonym Protein Names
MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1
UniProt Synonym Gene Names
NCBI Summary for MNK1
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]
UniProt Comments for MNK1
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Product References and Citations for anti-MNK1 antibody
Fukunaga R., EMBO J. 16:1921-1933(1997). Knauf U., Mol. Cell. Biol. 21:5500-5511(2001). O'Loghlen A., Exp. Cell Res. 299:343-355(2004).
Research Articles on MNK1
Precautions
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Products associated with anti-MNK1 antibody
Pathways associated with anti-MNK1 antibody
Diseases associated with anti-MNK1 antibody
Organs/Tissues associated with anti-MNK1 antibody
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