NP_998771.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
53,075 Da
NCBI Official Full Name
monocarboxylate transporter 12
NCBI Official Synonym Full Names
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
NCBI Official Synonym Symbols
NCBI Protein Information
monocarboxylate transporter 12
UniProt Protein Name
Monocarboxylate transporter 12
UniProt Synonym Protein Names
Solute carrier family 16 member 12
UniProt Synonym Gene Names
UniProt Entry Name
MOT12_HUMAN
NCBI Summary for MOT12
This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010]
UniProt Comments for MOT12
SLC16A12: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG). Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 10q23.31
Cellular Component: integral to plasma membrane
Molecular Function: creatine transporter activity; symporter activity; lactate transmembrane transporter activity
Disease: Cataract, Juvenile, With Microcornea And Glucosuria
Research Articles on MOT12
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Diseases associated with anti-MOT12 antibody
Organs/Tissues associated with anti-MOT12 antibody
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