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anti-MSK1 antibody :: Rabbit anti-Human, mouse MSK1 (Ab-581) Antibody

Scan QR to view Datasheet Catalog #    MBS002296 anti-MSK1 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MSK1 (Ab-581), Antibody

 Also Known As   

Rabbit MSK1 (Ab-581) Antibody

 Product Gene Name   

anti-MSK1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 14; NC_000014.8 (91337159..91526993, complement). Location: 14q31-q32.1
 OMIM    603607
 3D Structure    ModBase 3D Structure for O75582
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 Host    Rabbit
 Species Reactivity    Human, mouse
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 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Other Notes    Small volumes of anti-MSK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MSK1 antibody   

ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for MSK1. It may not necessarily be applicable to this product.
 NCBI GI #    32528295
 NCBI GeneID    9252
 NCBI Accession #    NP_004746.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004755.2 [Other Products]
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 UniProt Primary Accession #    O75582 [Other Products]
 UniProt Secondary Accession #    O95316; Q96AF7 [Other Products]
 UniProt Related Accession #    O75582 [Other Products]
 Molecular Weight    89,865 Da
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 NCBI Official Full Name    ribosomal protein S6 kinase alpha-5 isoform a
 NCBI Official Synonym Full Names    ribosomal protein S6 kinase, 90kDa, polypeptide 5
 NCBI Official Symbol    RPS6KA5 [Similar Products]
 NCBI Official Synonym Symbols   
MSK1; RLPK; MSPK1
[Similar Products]
 NCBI Protein Information    ribosomal protein S6 kinase alpha-5; RSKL; S6K-alpha-5; RSK-like protein kinase; 90 kDa ribosomal protein S6 kinase 5; nuclear mitogen- and stress-activated protein kinase 1
 UniProt Protein Name    Ribosomal protein S6 kinase alpha-5
 UniProt Synonym Protein Names   
90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase
 UniProt Gene Name    RPS6KA5 [Similar Products]
 UniProt Synonym Gene Names    MSK1; S6K-alpha-5; RSKL [Similar Products]
 UniProt Entry Name    KS6A5_HUMAN
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 UniProt Comments for MSK1    MSK1: an AGC kinase of the RSK family. Has two kinase domains connected by a regulatory linker region. Enzyme activity requires the presence of both kinase domains. Is phosphorylated and activated by Erk as well as p38 MAPK in response to growth factors and cellular stress.

Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, AGC; AGC group; RSK family; MSK subfamily

Chromosomal Location of Human Ortholog: 14q31-q32.1

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; magnesium ion binding; ATP binding; protein kinase activity

Biological Process: axon guidance; nerve growth factor receptor signaling pathway; positive regulation of histone phosphorylation; histone phosphorylation; stress-activated MAPK cascade; toll-like receptor 3 signaling pathway; protein amino acid phosphorylation; activation of NF-kappaB transcription factor; toll-like receptor 10 signaling pathway; toll-like receptor 5 signaling pathway; regulation of transcription, DNA-dependent; inflammatory response; toll-like receptor 4 signaling pathway; epidermal growth factor receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; activation of CREB transcription factor; toll-like receptor 2 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; negative regulation of cytokine production; toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of histone acetylation; toll-like receptor 9 signaling pathway; negative regulation of transcription, DNA-dependent
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 Research Articles on MSK1    1. Astaxanthin attenuates the UVB-induced secretion of prostaglandin E2 and interleukin-8 in human keratinocytes by interrupting MSK1 phosphorylation in a ROS depletion-independent manner
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MSK1 antibodyPathways associated with anti-MSK1 antibody
 Reference Product  PubMed Publications
 BAD antibody  >1 publications with MSK1 and BAD
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 CREB Phosphorylation Pathway antibodies  CREB Phosphorylation Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
Organs/Tissues associated with anti-MSK1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with MSK1 and Brain
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