NP_001229696.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,804 Da
NCBI Official Full Name
monofunctional C1-tetrahydrofolate synthase, mitochondrial isoform 1
NCBI Official Synonym Full Names
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
NCBI Protein Information
monofunctional C1-tetrahydrofolate synthase, mitochondrial
UniProt Protein Name
Monofunctional C1-tetrahydrofolate synthase, mitochondrial
UniProt Synonym Protein Names
Formyltetrahydrofolate synthetase
UniProt Synonym Gene Names
NCBI Summary for MTHFD1L
The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]
UniProt Comments for MTHFD1L
May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2.
Research Articles on MTHFD1L
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Products associated with anti-MTHFD1L antibody
Pathways associated with anti-MTHFD1L antibody
Diseases associated with anti-MTHFD1L antibody
Organs/Tissues associated with anti-MTHFD1L antibody
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