NP_001184110.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
tubulin beta-3 chain isoform 2
NCBI Official Synonym Full Names
tubulin beta 3 class III
NCBI Official Synonym Symbols
CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A [Similar Products]
NCBI Protein Information
tubulin beta-3 chain
UniProt Protein Name
Tubulin beta-3 chain
UniProt Synonym Protein Names
Tubulin beta-4 chain; Tubulin beta-III
UniProt Synonym Gene Names
NCBI Summary for TUBA1A
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Oct 2010]
UniProt Comments for TUBA1A
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Research Articles on TUBA1A
Precautions
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Pathways associated with anti-TUBA1A antibody
Diseases associated with anti-TUBA1A antibody
Disease Name |
Pubmed Publications |
Fibrosis Of Extraocular Muscles, Congenital, 3A, with or without Extraocular Involvement Antibodies |
>514 publications with TUBA1A and Fibrosis Of Extraocular Muscles, Congenital, 3A, with or without Extraocular Involvement |
Neoplasms Antibodies |
>47 publications with TUBA1A and Neoplasms |
Nervous System Diseases Antibodies |
>16 publications with TUBA1A and Nervous System Diseases |
Ovarian Neoplasms Antibodies |
>12 publications with TUBA1A and Ovarian Neoplasms |
Breast Neoplasms Antibodies |
>9 publications with TUBA1A and Breast Neoplasms |
Fibrosis Antibodies |
>8 publications with TUBA1A and Fibrosis |
Neoplasms, Experimental Antibodies |
>5 publications with TUBA1A and Neoplasms, Experimental |
Brain Diseases Antibodies |
>4 publications with TUBA1A and Brain Diseases |
Carcinoma, Squamous Cell Antibodies |
>4 publications with TUBA1A and Carcinoma, Squamous Cell |
Eye Diseases Antibodies |
>4 publications with TUBA1A and Eye Diseases |
Organs/Tissues associated with anti-TUBA1A antibody
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