Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ADORA2A rightarrow Monoclonal [7F6-G5-A2 / 7F6] ADORA2A  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • preptin ELISA Kit
 • CD339 Antibody
 • MYO3A Antibody
 • A-kinase anchor protein 9 (AKAP9) ELISA Kit
 • SCTR - SR - Secretin Receptor Antibody
 • Reduced Glutathione (GSH) ELISA Kit
 • Type-1A angiotensin II receptor (Agtr1a) ELISA Kit
 • Platelet Antibody (APAB) ELISA Kit
 • Melanosome (PMEL) Antibody
 • CRLF3 Antibody
 • REN (Renin) ELISA Kit
 • Adropin ELISA Kit
 • BANF1 Antibody
 • Troponin Complex-Cardiac, Rat Native Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ADORA2A antibody :: Mouse ADORA2A/Adenosine A2A Receptor Monoclonal [7F6-G5-A2 / 7F6] Antibody

Scan QR to view Datasheet Catalog #    MBS245206
Immunohistochemistry (IHC)
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ADORA2A/Adenosine A2A Receptor, Monoclonal [7F6-G5-A2 / 7F6] Antibody

★Popular Item★
 Also Known As   

Mouse Monoclonal (IgG2a) to Human ADORA2A/Adenosine A2A Receptor

 Product Synonym Names    Anti-ADORA2A/Adenosine A2A Receptor Antibody (3rd Intracellular Domain) IHC-plus; Adenosine receptor A2a; ADORA2; A2a receptor; Adenosine A2a receptor; Adenosine A2 receptor; Adenosine receptor subtype A2a; HA2aR; RDC8; Human ADORA2A/Adenosine A2A Receptor
 Product Gene Name   

anti-ADORA2A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    102776
 3D Structure    ModBase 3D Structure for P29274
Section Bar
 Clonality    Monoclonal [7F6-G5-A2 / 7F6]
 Isotype    IgG2a
 Host    Mouse
 Species Reactivity    Dog, Guinea pig, Human, Mouse, Rabbit, Rat
Section Bar
 Specificity    Recognizes human adenosine receptor A2A at ~43kD.
 Purity/Purification    Protein G Purified
 Form/Format    0.01M Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide
 Concentration    0.5 mg/ml (lot specific)
Section Bar
 Target Species    Human
 Immunogen Description    6His-tagged full-length human recombinant A2A receptor. Epitope mapped to SQPLPGER in the third intracellular loop.
 Immunogen Type    Recombinant protein
 Immunogen    ADORA2A/Adenosine A2A Receptor antibody was raised against 6His-tagged full-length human recombinant A2A receptor. Epitope mapped to SQPLPGER in the third intracellular loop.
 Antigen Modification    3rd Intracellular Domain
Section Bar
 Preparation and Storage    Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
 Other Notes    Small volumes of anti-ADORA2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-ADORA2A antibody

   The A2a Adenosine Receptor is a major target of caffeine. This receptor inhibits cell aggregation, induces vasodilation, and downregulates inflammation.
 Product Categories/Family for anti-ADORA2A antibody    Family: GPCR
Subfamily: Adenosine
 Applications Tested/Suitable for anti-ADORA2A antibody   

Immunohistochemistry (IHC - Paraffin; IHC - 4% paraformaldehyde), Western Blot (WB), Flow Cytometry (FC/FACS)

 Application Notes for anti-ADORA2A antibody    Flo, IHC-P (5 ug/ml), IHC-Pfa (1 ug/ml), WB (1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Section Bar
 Immunohistochemistry (IHC) of anti-ADORA2A antibody    Anti-ADORA2A antibody IHC of human brain, putamen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-ADORA2A antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ADORA2A. It may not necessarily be applicable to this product.
 NCBI GI #    5921992
 NCBI GeneID    135
 NCBI Accession #    NP_000666.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000675.5 [Other Products]
Section Bar
 UniProt Primary Accession #    P29274 [Other Products]
 UniProt Secondary Accession #    B2R7E0 [Other Products]
 UniProt Related Accession #    P29274 [Other Products]
 Molecular Weight    44,707 Da
Table BarTOPTable Bar
 NCBI Official Full Name    adenosine receptor A2a
 NCBI Official Synonym Full Names    adenosine A2a receptor
 NCBI Official Symbol    ADORA2A [Similar Products]
 NCBI Official Synonym Symbols   
A2aR; RDC8; ADORA2
[Similar Products]
 NCBI Protein Information    adenosine receptor A2a; adenosine receptor subtype A2a
 UniProt Protein Name    Adenosine receptor A2a
 Protein Family    Adenosine receptor
 UniProt Gene Name    ADORA2A [Similar Products]
 UniProt Synonym Gene Names    ADORA2 [Similar Products]
 UniProt Entry Name    AA2AR_HUMAN
Section Bar
 NCBI Summary for ADORA2A    This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
Section Bar
 UniProt Comments for ADORA2A    ADORA2A: one of several receptor subtypes for adenosine. A G-protein coupled receptor. Activation is mediated by G proteins which activate adenylyl cyclase. Abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q11.23

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: identical protein binding; protein binding; enzyme binding; adenosine receptor activity, G-protein coupled

Biological Process: central nervous system development; nerve growth factor receptor signaling pathway; apoptosis; blood circulation; adenylate cyclase activation; phagocytosis; G-protein signaling, coupled to cAMP nucleotide second messenger; cell-cell signaling; sensory perception; cellular defense response; cAMP biosynthetic process; inflammatory response; blood coagulation; adenosine receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway
Table BarTOPTable Bar
 Research Articles on ADORA2A    1. novel approach consisting in the integration of molecular docking and membrane molecular dynamics simulations of the A(2A) adenosine receptor and ligands
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-ADORA2A antibodyPathways associated with anti-ADORA2A antibody
 Reference Product  PubMed Publications
 ADM antibody  >2 publications with ADORA2A and ADM
 DRD5 antibody  >2 publications with ADORA2A and DRD5
 DRD1 antibody  >2 publications with ADORA2A and DRD1
 Products by Pathway  Pathway Diagram
 Activation Of TRKA Receptors Pathway antibodies  Activation Of TRKA Receptors Pathway Diagram
 Adenosine P1 Receptors Pathway antibodies  Adenosine P1 Receptors Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
Diseases associated with anti-ADORA2A antibodyOrgans/Tissues associated with anti-ADORA2A antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >20 publications with ADORA2A and Inflammation
 Genetic Predisposition to Disease Antibodies  >18 publications with ADORA2A and Genetic Predisposition to Disease
 Anxiety Disorders Antibodies  >10 publications with ADORA2A and Anxiety Disorders
 Disease Models, Animal Antibodies  >10 publications with ADORA2A and Disease Models, Animal
 Movement Disorders Antibodies  >7 publications with ADORA2A and Movement Disorders
 Panic Disorder Antibodies  >6 publications with ADORA2A and Panic Disorder
 Parkinson Disease Antibodies  >3 publications with ADORA2A and Parkinson Disease
 Cognition Disorders Antibodies  >3 publications with ADORA2A and Cognition Disorders
 Hypertension Antibodies  >3 publications with ADORA2A and Hypertension
 Amphetamine-Related Disorders Antibodies  >2 publications with ADORA2A and Amphetamine-Related Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >32 publications with ADORA2A and Brain
 Blood Antibodies  >21 publications with ADORA2A and Blood
 Vascular Antibodies  >9 publications with ADORA2A and Vascular
 Lung Antibodies  >5 publications with ADORA2A and Lung
 Eye Antibodies  >4 publications with ADORA2A and Eye
 Liver Antibodies  >3 publications with ADORA2A and Liver
 Heart Antibodies  >2 publications with ADORA2A and Heart
 Embryonic Tissue Antibodies  >2 publications with ADORA2A and Embryonic Tissue
 Intestine Antibodies  >1 publications with ADORA2A and Intestine
 Stomach Antibodies  >1 publications with ADORA2A and Stomach
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions