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anti-14-3-3 antibody :: Mouse 14-3-3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS845477 anti-14-3-3 antibody
Unit / Price
0.1 mg  /  $270 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3, Monoclonal Antibody

 Also Known As   

14-3-3 monoclonal Antibody

 Product Synonym Names    14 3 3 antibody; 14 3 3 protein beta antibody; 14 3 3 protein beta/alpha antibody; 14 3 3 protein zeta antibody; 14 3 3 zeta antibody; 14-3-3 protein beta/alpha antibody; 14-3-3 protein/cytosolic phospholipase A2 antibody; GW128 antibody; HS1 antibody; KCIP 1 antibody; MGC111427 antibody; MGC126532 antibody; MGC138156 antibody; Protein 1054 antibody; Protein kinase C inhibitor protein 1 antibody; Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein delta polypeptide antibody; Tyrosine 3/tryptophan 5-monooxygenase activation protein; zeta polypeptide antibody; YWHAB antibody; YWHAD antibody; YWHAZ antibody; YWHAZ antibody
 Product Gene Name   

anti-14-3-3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P29310
 Clonality    Monoclonal
 Isotype    IgG
 Host    Mouse
 Species Reactivity    Human, Mouse, Rat, Pig, Monkey, Rabbit, Dog, Sheep, Bovine
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 Purity/Purification    Affinity Purified
 Form/Format    Colorless liquid
100 ug (0.5 mg/ml) immunoaffinity purified mouse monoclonal antibody in PBS containing 1 mg/ml BSA and 1.5 mM sodium azide and 50% glycerol.
 Concentration    0.5 mg/ml (lot specific)
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 Preparation and Storage    Store at -20 degree C for 12 months.
The antibody solution should be gently mixed before use.
 Other Notes    Small volumes of anti-14-3-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-14-3-3 antibody

   The 14-3-3 proteins comprise a family of highly conserved acidic proteins which play a role in both signal transduction and the cell cycle by binding to and regulating several different proteins. The family of proteins is present in particularly high concentrations in mammalian brain and may be involved in the regulation of neuronal activity. The 14-3-3 proteins exist as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C.
 Product Categories/Family for anti-14-3-3 antibody    14-3-3
 Applications Tested/Suitable for anti-14-3-3 antibody   

Western Blot (WB)

 Application Notes for anti-14-3-3 antibody    Western Blot: 1-4 ug
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NCBI/Uniprot data below describe general gene information for 14-3-3. It may not necessarily be applicable to this product.
 NCBI GI #    62471695
 NCBI GeneID    36059
 NCBI Accession #    NP_001014515.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001014515.2 [Other Products]
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 UniProt Primary Accession #    P29310 [Other Products]
 UniProt Secondary Accession #    O01665; Q0E9D5; Q0E9D6; Q0E9D7; Q8IGB9; Q8MKV5; Q9V5G6; A4UZB2; A4UZB3; C1C593; C9QP27 [Other Products]
 UniProt Related Accession #    P29310 [Other Products]
 Molecular Weight    28,304 Da
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 NCBI Official Full Name    14-3-3zeta, isoform J
 NCBI Official Symbol    14-3-3zeta [Similar Products]
 NCBI Official Synonym Symbols   
14-3-3; 14-3-3 zeta; 14-3-3-Leo; 14-3-3-zeta; 14-3-3leo; 14-3-3ZETA; 2G1; 4-3-3 zeta; 5.11; 549; BEST:GH05075; CG17870; D14-3-3; d14-3-3zeta; D14-3-3zeta; DmelCG17870; K; l(2)07103; l(2)46CFe; l(2)46Ee; leo; Leo; LEO; par-5; Par-5; PAR-5; PAR5
[Similar Products]
 NCBI Protein Information    CG17870 gene product from transcript CG17870-RE
 UniProt Protein Name    14-3-3 protein zeta
 UniProt Synonym Protein Names   
14-3-3-like protein; Protein Leonardo
 Protein Family    14-3-3 protein
 UniProt Gene Name    14-3-3zeta [Similar Products]
 UniProt Synonym Gene Names    14-3-3; 14-3-3EZ; leo; THAP [Similar Products]
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 UniProt Comments for 14-3-3    Required in Raf-dependent cell proliferation and photoreceptor differentiation during eye development (PubMed:9159395). Acts upstream of Raf and downstream of Ras, and is essential for viability (PubMed:9159395). Acts as a negative regulator of the slo calcium channel via its interaction with slo-binding protein slob (PubMed:10230800). Inhibits yki activity by restricting its nuclear localization (PubMed:19900439). Binds to and promotes the activity of phosphoinositide 3-kinase Pi3K68D which converts phosphatidylinositol to phosphatidylinositol-3-phosphate and promotes maturation of early endosomes (PubMed:27015288).
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 Research Articles on 14-3-3    1. The Khc73 stalk/14-3-3/NudE pathway defines a physical connection that coordinates the activities of multiple motor proteins to precisely position the spindle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-14-3-3 antibodyDiseases associated with anti-14-3-3 antibody
 Products by Pathway  Pathway Diagram
 Hippo Signaling Pathway - Fly antibodies  Hippo Signaling Pathway - Fly Diagram
 Hippo Signaling Pathway - Fly antibodies  Hippo Signaling Pathway - Fly Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies  Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram
 Disease Name  Pubmed Publications
 Death Antibodies  >37 publications with 14-3-3 and Death
 Brain Diseases Antibodies  >18 publications with 14-3-3 and Brain Diseases
 Disease Models, Animal Antibodies  >11 publications with 14-3-3 and Disease Models, Animal
 Seizures Antibodies  >7 publications with 14-3-3 and Seizures
 Epilepsy Antibodies  >6 publications with 14-3-3 and Epilepsy
 Autoimmune Diseases Antibodies  >3 publications with 14-3-3 and Autoimmune Diseases
 Kidney Diseases Antibodies  >3 publications with 14-3-3 and Kidney Diseases
 Cognition Disorders Antibodies  >3 publications with 14-3-3 and Cognition Disorders
 Brain Injuries Antibodies  >2 publications with 14-3-3 and Brain Injuries
 Status Epilepticus Antibodies  >2 publications with 14-3-3 and Status Epilepticus
Organs/Tissues associated with anti-14-3-3 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >44 publications with 14-3-3 and Blood
 Ovary Antibodies  >9 publications with 14-3-3 and Ovary
 Head Antibodies  >8 publications with 14-3-3 and Head
 Embryonic Tissue Antibodies  >5 publications with 14-3-3 and Embryonic Tissue
 Testis Antibodies  >3 publications with 14-3-3 and Testis
 Fat Body Antibodies  >2 publications with 14-3-3 and Fat Body
 Uncharacterized Tissue Antibodies  >2 publications with 14-3-3 and Uncharacterized Tissue
 Gonad Antibodies  >1 publications with 14-3-3 and Gonad
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