Q02338
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
3-hydroxybutyrate dehydrogenase, type 1
NCBI Official Synonym Full Names
3-hydroxybutyrate dehydrogenase, type 1
NCBI Official Synonym Symbols
BDH; SDR9C1; MGC2723; MGC4347; MGC9788 [Similar Products]
NCBI Protein Information
D-beta-hydroxybutyrate dehydrogenase, mitochondrial; OTTHUMP00000208056; OTTHUMP00000208057; OTTHUMP00000208058; OTTHUMP00000208059; (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); short chain dehydrogenase/reductase family 9C, member 1
UniProt Protein Name
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
UniProt Synonym Protein Names
3-hydroxybutyrate dehydrogenase
UniProt Synonym Gene Names
UniProt Entry Name
BDH_HUMAN
NCBI Summary for BDH1
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
UniProt Comments for BDH1
BDH: a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Protein type: Mitochondrial; Lipid Metabolism - synthesis and degradation of ketone bodies; Oxidoreductase; EC 1.1.1.30; Carbohydrate Metabolism - butanoate
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; cytoplasm; mitochondrial inner membrane
Molecular Function: 3-hydroxybutyrate dehydrogenase activity; phospholipid binding
Biological Process: response to drug; response to toxin; ketone body metabolic process; cellular lipid metabolic process; liver development; response to estradiol stimulus; response to insulin stimulus; response to starvation; response to cadmium ion; response to ethanol; ketone body catabolic process; ketone body biosynthetic process; brain development; response to nutrient; response to corticosterone stimulus
Research Articles on BDH1
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Pathways associated with anti-BDH1 antibody
Diseases associated with anti-BDH1 antibody
Organs/Tissues associated with anti-BDH1 antibody
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