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anti-ADAMTS1 antibody :: Mouse anti-Human A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2012517 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Western Blot (WB)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $110 +1 FREE 8GB USB
0.05 mg  /  $145 +1 FREE 8GB USB
0.1 mg  /  $175 +1 FREE 8GB USB
0.2 mg  /  $230 +1 FREE 8GB USB
1 mg  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1), Monoclonal Antibody

★Popular Item★
 Also Known As   

Monoclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1)

 Product Gene Name   

anti-ADAMTS1 antibody

[Similar Products]
 Matching Pairs    Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
Antigen: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012165)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
APC: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2061324)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
PE Conjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2061328)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
APC: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2061332)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
Cy3 Conjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2061335)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
FITC Conjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2061339)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
HRP Conjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2061343)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
Biotin Conjugated Secondary Antibody: IgG (MBS2086030)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
FITC Conjugated Secondary Antibody: IgG (MBS2086031)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
Biotin Conjugated Secondary Antibody: IgG (MBS2086033)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
FITC Conjugated Secondary Antibody: IgG (MBS2086034)
 Matching Pairs    Unconjugated Antibody: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (MBS2012517)
HRP Conjugated Secondary Antibody: IgG (MBS2086035)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG S-DLPGT SYDANRQCQF TFGEDSKHCP DAASTCSTLW CTGTSGGVLV CQTKHFPWAD GTSCGEGKWC INGKCVNKTD RKHFDTPFHG SWGMWGPWGD CSRTCGGGVQ YTMRECDNPV PKNGGKYCEG KRVRYRSCNL EDCP
 OMIM    AF170084 mRNA
 3D Structure    ModBase 3D Structure for Q9UHI8
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 Clonality    Monoclonal
 Isotype    IgG
 Host    Mouse
 Species Reactivity    Human
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 Specificity    The antibody is a mouse monoclonal antibody raised against ADAMTS1. It has been selected for its ability to recognize ADAMTS1 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    500ug/ml (lot specific)
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 Immunogen    Recombinant ADAMTS1 (Asp476~Pro614) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2061332
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-ADAMTS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ADAMTS1 antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-ADAMTS1 antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-ADAMTS1 antibody    (Figure. Western Blot; Sample: Recombinant ADAMTS1, Human.)
anti-ADAMTS1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ADAMTS1. It may not necessarily be applicable to this product.
 NCBI GI #    50845384
 NCBI GeneID    9510
 NCBI Accession #    NP_008919.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_006988.4 [Other Products]
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 UniProt Primary Accession #    Q9UHI8 [Other Products]
 UniProt Secondary Accession #    Q9NSJ8; Q9P2K0; Q9UH83; Q9UP80; D3DSD5 [Other Products]
 UniProt Related Accession #    Q9UHI8 [Other Products]
 Molecular Weight    105,358 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 1 preproprotein
 NCBI Official Synonym Full Names    ADAM metallopeptidase with thrombospondin type 1 motif 1
 NCBI Official Symbol    ADAMTS1 [Similar Products]
 NCBI Official Synonym Symbols   
C3-C5; METH1
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 1
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 1
 UniProt Synonym Protein Names   
METH-1
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    ADAMTS1 [Similar Products]
 UniProt Synonym Gene Names    KIAA1346; METH1; ADAM-TS 1; ADAM-TS1; ADAMTS-1 [Similar Products]
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 NCBI Summary for ADAMTS1    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADAMTS1    ADAMTS1: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.

Protein type: EC 3.4.24.-; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 21q21.3

Cellular Component: basement membrane; cytoplasmic vesicle; cytosol

Molecular Function: heparin binding; metalloendopeptidase activity; metallopeptidase activity; zinc ion binding

Biological Process: integrin-mediated signaling pathway; kidney development; negative regulation of cell proliferation; ovulation from ovarian follicle; proteolysis
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 Research Articles on ADAMTS1    1. Adamts1 acts as an extracellular matrix 'modifier', with miR-181d-induced downregulation, that regulates adipocyte lineage commitment and obesity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADAMTS1 antibodyPathways associated with anti-ADAMTS1 antibody
 Reference Product  PubMed Publications
 FURIN antibody  >9 publications with ADAMTS1 and FURIN
 VCAN antibody  >6 publications with ADAMTS1 and VCAN
 VEGFA antibody  >5 publications with ADAMTS1 and VEGFA
 FGF2 antibody  >3 publications with ADAMTS1 and FGF2
 ACAN antibody  >2 publications with ADAMTS1 and ACAN
 Products by Pathway  Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
Diseases associated with anti-ADAMTS1 antibodyOrgans/Tissues associated with anti-ADAMTS1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >62 publications with ADAMTS1 and Neoplasms
 Inflammation Antibodies  >17 publications with ADAMTS1 and Inflammation
 Necrosis Antibodies  >13 publications with ADAMTS1 and Necrosis
 Neoplasms, Experimental Antibodies  >13 publications with ADAMTS1 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >11 publications with ADAMTS1 and Breast Neoplasms
 Kidney Diseases Antibodies  >10 publications with ADAMTS1 and Kidney Diseases
 Fibrosis Antibodies  >8 publications with ADAMTS1 and Fibrosis
 Brain Diseases Antibodies  >7 publications with ADAMTS1 and Brain Diseases
 Lung Neoplasms Antibodies  >7 publications with ADAMTS1 and Lung Neoplasms
 Lung Diseases Antibodies  >6 publications with ADAMTS1 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >60 publications with ADAMTS1 and Vascular
 Ovary Antibodies  >30 publications with ADAMTS1 and Ovary
 Bone Antibodies  >27 publications with ADAMTS1 and Bone
 Muscle Antibodies  >23 publications with ADAMTS1 and Muscle
 Heart Antibodies  >22 publications with ADAMTS1 and Heart
 Connective Tissue Antibodies  >22 publications with ADAMTS1 and Connective Tissue
 Kidney Antibodies  >22 publications with ADAMTS1 and Kidney
 Brain Antibodies  >17 publications with ADAMTS1 and Brain
 Embryonic Tissue Antibodies  >16 publications with ADAMTS1 and Embryonic Tissue
 Lung Antibodies  >11 publications with ADAMTS1 and Lung
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