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anti-ADAMTS2 antibody :: Mouse anti-Bovine A Disintegrin And Metalloproteinase With Thrombospondin 2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2025821 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Western Blot (WB)
Unit / Price
0.02 mg  /  $150 +1 FREE 8GB USB
0.1 mg  /  $280 +1 FREE 8GB USB
0.2 mg  /  $395 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2), Monoclonal Antibody

 Also Known As   

Monoclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 2 (ADAMTS2)

 Product Gene Name   

anti-ADAMTS2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG S-QLPGLHY SMNEQCRFDF GLGYMMCTAF RTFDPCKQLW CSHPDNPYFC KTKKGPPLDG TMCAPGKHCF KGHCIWLTPD ILKRDGNWGA
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 Clonality    Monoclonal
 Isotype    IgG
 Host    Mouse
 Species Reactivity    Bovine
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 Specificity    The antibody is a mouse monoclonal antibody raised against ADAMTS2. It has beenselected for its ability to recognize ADAMTS2 in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Concentration    500ug/ml (lot specific)
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 Organism Species    Bos taurus; Bovine (Cattle)
 Conjugate    No Conjugate
 Immunogen    Recombinant ADAMTS2 (Gln474~Pro610) expressed in E Coli.
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-ADAMTS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ADAMTS2 antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

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 Western Blot (WB) of anti-ADAMTS2 antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-ADAMTS2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ADAMTS2. It may not necessarily be applicable to this product.
 NCBI GI #    33563307
 NCBI GeneID    216725
 NCBI Accession #    NP_783574.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_175643.3 [Other Products]
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 UniProt Related Accession #    Q8C9W3 [Other Products]
 Molecular Weight    135,299 Da
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 NCBI Official Full Name    A disintegrin and metalloproteinase with thrombospondin motifs 2 preproprotein
 NCBI Official Synonym Full Names    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
 NCBI Official Symbol    Adamts2 [Similar Products]
 NCBI Official Synonym Symbols   
pNPI; PCINP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAM-TS 2
[Similar Products]
 NCBI Protein Information    A disintegrin and metalloproteinase with thrombospondin motifs 2
 UniProt Protein Name    A disintegrin and metalloproteinase with thrombospondin motifs 2
 UniProt Synonym Protein Names   
Procollagen I N-proteinase; PC I-NP; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase; pNPI
 Protein Family    A disintegrin and metalloproteinase with thrombospondin motifs
 UniProt Gene Name    Adamts2 [Similar Products]
 UniProt Synonym Gene Names    ADAM-TS 2; ADAM-TS2; ADAMTS-2; PC I-NP; pNPI [Similar Products]
 UniProt Entry Name    ATS2_MOUSE
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 NCBI Summary for ADAMTS2    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin repeats) family of proteinases that is involved in the proteolytic processing of procollagens. The encoded protein precursor is proteolytically processed to generate a mature, zinc-dependent enzyme. Mice lacking the encoded protein develop abnormal lungs, fragile skin and male sterility. [provided by RefSeq, Aug 2015]
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 UniProt Comments for ADAMTS2    ADAMTS2: Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis. Defects in ADAMTS2 are the cause of Ehlers-Danlos syndrome type 7C (EDS7C). EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity. EDS7C is marked by extremely fragile tissues, hyperextensible skin and easy bruising. Facial skin contains numerous folds, as in the cutis laxa syndrome. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Extracellular matrix; Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide; EC 3.4.24.14; Protease

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region

Molecular Function: peptidase activity; hydrolase activity; zinc ion binding; metallopeptidase activity; metal ion binding; metalloendopeptidase activity

Biological Process: skin development; collagen catabolic process; collagen fibril organization; spermatogenesis; protein processing; proteolysis; lung development
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 Research Articles on ADAMTS2    1. There is no significant genotype effect of ADAMTS2 on age, height, weight, BMI or sex on risk of Achilles tendon pathology.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADAMTS2 antibodyPathways associated with anti-ADAMTS2 antibody
 Reference Product  PubMed Publications
 Col1a1 antibody  >4 publications with ADAMTS2 and Col1a1
 Col3a1 antibody  >3 publications with ADAMTS2 and Col3a1
 Col5a1 antibody  >3 publications with ADAMTS2 and Col5a1
 Fbn1 antibody  >2 publications with ADAMTS2 and Fbn1
 Col1a2 antibody  >2 publications with ADAMTS2 and Col1a2
 Pcolce2 antibody  >1 publications with ADAMTS2 and Pcolce2
 Pcolce antibody  >1 publications with ADAMTS2 and Pcolce
 Products by Pathway  Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with anti-ADAMTS2 antibodyOrgans/Tissues associated with anti-ADAMTS2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >3 publications with ADAMTS2 and Inflammation
 Necrosis Antibodies  >3 publications with ADAMTS2 and Necrosis
 Fibrosis Antibodies  >2 publications with ADAMTS2 and Fibrosis
 Carcinoma Antibodies  >2 publications with ADAMTS2 and Carcinoma
 Breast Neoplasms Antibodies  >1 publications with ADAMTS2 and Breast Neoplasms
 Liver Diseases Antibodies  >1 publications with ADAMTS2 and Liver Diseases
 Precancerous Conditions Antibodies  >1 publications with ADAMTS2 and Precancerous Conditions
 Disease Models, Animal Antibodies  >1 publications with ADAMTS2 and Disease Models, Animal
 Hyperplasia Antibodies  >1 publications with ADAMTS2 and Hyperplasia
 Hypertension Antibodies  >1 publications with ADAMTS2 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >10 publications with ADAMTS2 and Skin
 Joint Antibodies  >4 publications with ADAMTS2 and Joint
 Embryonic Tissue Antibodies  >4 publications with ADAMTS2 and Embryonic Tissue
 Bone Antibodies  >3 publications with ADAMTS2 and Bone
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