NP_005882
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,643 Da
NCBI Official Full Name
acetyl-CoA acetyltransferase, cytosolic isoform 1
NCBI Official Synonym Full Names
acetyl-CoA acetyltransferase 2
NCBI Protein Information
acetyl-CoA acetyltransferase, cytosolic
UniProt Protein Name
Acetyl-CoA acetyltransferase, cytosolic
UniProt Synonym Protein Names
Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase
UniProt Synonym Gene Names
UniProt Entry Name
THIC_HUMAN
NCBI Summary for ACAT2
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
UniProt Comments for ACAT2
ACAT2: The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008]
Protein type: Lipid Metabolism - synthesis and degradation of ketone bodies; Lipid Metabolism - fatty acid; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 2.3.1.9; Amino Acid Metabolism - lysine degradation; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - tryptophan; Acetyltransferase; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate
Chromosomal Location of Human Ortholog: 6q25.3
Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus
Molecular Function: acetyl-CoA C-acetyltransferase activity
Biological Process: lipid metabolic process
Disease: Acetyl-coa Acetyltransferase-2 Deficiency
Research Articles on ACAT2
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Products associated with anti-ACAT2 antibody
Pathways associated with anti-ACAT2 antibody
Diseases associated with anti-ACAT2 antibody
Organs/Tissues associated with anti-ACAT2 antibody
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