Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow AK3 rightarrow Monoclonal AK3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Heat Shock Protein 90, alpha (HSP90AB1) Antibody
 • D-Dimer (D2D) ELISA Kit
 • Parathyroid hormone protein (PTH),15N Stable Isotope Labeled Recombinant Protein
 • 15 (S) -Hydroxyeicosatetraenoic Acid (15-S-HETE) ELISA Kit
 • Thy 1.1 Lyophilized Antibody
 • gp120 (env) Antibody
 • Complement C3 (C3) Recombinant Protein
 • CX31 ELISA Kit
 • Solute carrier family 40 member 1 (SLC40A1) ELISA Kit
 • basic Fibroblast Growth Factor (bFGF) Recombinant Protein
 • 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (is... Recombinant Protein
 • Insulin C-terminal Pentapeptide of B-chain Antibody
 • DPPA3 Recombinant Protein
 • Bcl-2-like protein 1 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-AK3 antibody :: Mouse anti-Human, Mouse AK3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS200020
Unit / Price
0.05 mL  /  $260 +1 FREE 8GB USB
0.1 mL  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AK3, Monoclonal Antibody

 Also Known As   

AK3 antibody

 Product Synonym Names    adenylate kinase; Ak6; FIX; Ak3L1; AkL3L; AkL3L1; adenylate kinase 3; adenylate kinase 6; adenylate kinase 3 like 1
 Product Gene Name   

anti-AK3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    AB021870 mRNA
 3D Structure    ModBase 3D Structure for Q9UIJ7
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1, k
 Clone Number    SJB3-36
 Host    Mouse
 Species Reactivity    Human, Mouse
Section Bar
 Purity/Purification    By protein-G affinity chromatography
 Form/Format    Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
 Concentration    1mg/ml (lot specific)
Section Bar
 Antigen Species    Human
 Immunogen    Recombinant human Ak3 (adenylaste kinase isozyme 3) purified from E. coli
 Clone Note    Anti-human Ak3 mAb, clone SJB3-36, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Ak3 protein.
Section Bar
 Preparation and Storage    Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of anti-AK3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-AK3 antibody

   Adenylate kinase (Ak; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phospho-transferase, EC 2.7.4.3) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (Ak1, Ak2 and Ak3) are characterized in vertebrates. Ak1 is present in the cytosol of skeletal muscle, brain, and erythrocyte, while Ak2 is localized in the intermembrane space of mitochondria of liver, kidney, spleen and heart. Ak3, called GTP:AMP phosphotransferase, exists in the mitochondrial matrix of liver and heart. These isozymes contribute to homeostasis of the adenine nucleotide composition in the cell.
 Product Categories/Family for anti-AK3 antibody    Signal Transduction
 Applications Tested/Suitable for anti-AK3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)

 Application Notes for anti-AK3 antibody    WB: 1:500 ~ 1:2,000.
Recommended starting dilution is 1:1,000.
Section Bar
 Western Blot (WB) of anti-AK3 antibody    The recombinant protein (50ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human AK3 antibody (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : Recombinant Human AK1 Lane 2. : Recombinant Human AK2 Lane 3. : Recombinant Human AK3 The lysate (40ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human AK3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : Hep3B cell lysate Lane 2. : 293T cell lysate Lane 3. : Mouse kidney tissue lysate The lysate (40ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human AK3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : Mouse liver tissue lysate
anti-AK3 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-AK3 antibody    Human liver tissue was incubated with anti-human Ak3 (1:100) for 2 hours at room temperature. Slide was then washed in PBS, and was incubated in avidin biosystem anti-rabbit labeled polymer for 30 min at RT. Enzyme detection was performed with DAB chromo-gen.
anti-AK3 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunofluorescence (IF) of anti-AK3 antibody    ICC/IF analysis of AK3 in U87MG cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human AK3 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
anti-AK3 antibody Immunofluorescence (IF) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for AK3. It may not necessarily be applicable to this product.
 NCBI GI #    19923437
 NCBI GeneID    50808
 NCBI Accession #    NP_057366 [Other Products]
 NCBI GenBank Nucleotide #    NM_016282.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9UIJ7 [Other Products]
 UniProt Secondary Accession #    Q5VYW6; Q9H576; Q9HC01; Q9NPB4; B4DP58; D3DRI1; E7ET30 [Other Products]
 UniProt Related Accession #    Q9UIJ7 [Other Products]
 Molecular Weight    21,014 Da
Table BarTOPTable Bar
 NCBI Official Full Name    GTP:AMP phosphotransferase AK3, mitochondrial isoform a
 NCBI Official Synonym Full Names    adenylate kinase 3
 NCBI Official Symbol    AK3 [Similar Products]
 NCBI Official Synonym Symbols   
AK6; FIX; AK3L1; AKL3L; AKL3L1
[Similar Products]
 NCBI Protein Information    GTP:AMP phosphotransferase AK3, mitochondrial
 UniProt Protein Name    GTP:AMP phosphotransferase AK3, mitochondrial
 UniProt Synonym Protein Names   
Adenylate kinase 3
 Protein Family    GTP:AMP phosphotransferase
 UniProt Gene Name    AK3 [Similar Products]
 UniProt Synonym Gene Names    AK 3 [Similar Products]
Section Bar
 NCBI Summary for AK3    The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Section Bar
 UniProt Comments for AK3    Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
Table BarTOPTable Bar
 

Product References and Citations for anti-AK3 antibody

   Noda, L.H. et al. (1973) The Enzymes. Vol. 8, 279-305; Khoo, J.C. et al. (1972) Biochim. Biophys. Acta 268, 98-101; Tomasselli, A.G. et al. (1979) Eur.J.Biochemolecules 93, 257-262; Lee, Y. et al. (1998) J. Biochem. 123, 47-54.
Section Bar
 Research Articles on AK3    1. These findings suggest that AK3 and SLIT2 may be potential candidates involved in genetic susceptibility to colorectal cancer
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-AK3 antibodyPathways associated with anti-AK3 antibody
 Reference Product  PubMed Publications
 NME1 antibody  >1 publications with AK3 and NME1
 NME6 antibody  >1 publications with AK3 and NME6
 NME4 antibody  >1 publications with AK3 and NME4
 Products by Pathway  Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
Diseases associated with anti-AK3 antibodyOrgans/Tissues associated with anti-AK3 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with AK3 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >3 publications with AK3 and Cardiovascular Diseases
 Brain Diseases Antibodies  >3 publications with AK3 and Brain Diseases
 Liver Neoplasms Antibodies  >2 publications with AK3 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with AK3 and Liver Diseases
 Neoplasm Metastasis Antibodies  >1 publications with AK3 and Neoplasm Metastasis
 Heart Diseases Antibodies  >1 publications with AK3 and Heart Diseases
 Fibrosis Antibodies  >1 publications with AK3 and Fibrosis
 Kidney Diseases Antibodies  >1 publications with AK3 and Kidney Diseases
 Inflammation Antibodies  >1 publications with AK3 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >13 publications with AK3 and Blood
 Liver Antibodies  >10 publications with AK3 and Liver
 Brain Antibodies  >10 publications with AK3 and Brain
 Heart Antibodies  >9 publications with AK3 and Heart
 Muscle Antibodies  >9 publications with AK3 and Muscle
 Kidney Antibodies  >5 publications with AK3 and Kidney
 Nerve Antibodies  >3 publications with AK3 and Nerve
 Embryonic Tissue Antibodies  >2 publications with AK3 and Embryonic Tissue
 Lung Antibodies  >2 publications with AK3 and Lung
 Ovary Antibodies  >2 publications with AK3 and Ovary
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions