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anti-AMY2A antibody :: Mouse AMYLASE Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS211456 anti-AMY2A antibody
Unit / Price
1 mg  /  $370 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AMYLASE (AMY2A), Monoclonal Antibody

 Also Known As   

MOUSE ANTI HUMAN AMYLASE

 Product Gene Name   

anti-AMY2A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    104650
 3D Structure    ModBase 3D Structure for P04746
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 Clonality    Monoclonal
 Isotype    IgM
 Clone Number    6A9/1
 Host    Mouse
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 Specificity    This item recognises human pancreatic amylase, a secreted enzyme that catalyses the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in oligosaccharides and polysaccharides.This antibody showns minimal cross-reactivity with salivary amylase.
 Form/Format    Purified
Ig fraction - liquid
 Concentration    IgM concentration 1.0 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
Preparation
 Immunogen    Native pancreatic amylase
Buffer Solution
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-AMY2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-AMY2A antibody

   MBS211456 recognises human pancreatic amylase, a secreted enzyme that catalyses the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in oligosaccharides and polysaccharides. This antibody showns minimal cross-reactivity with salivary amylase.
 Applications Tested/Suitable for anti-AMY2A antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for AMY2A. It may not necessarily be applicable to this product.
 NCBI GI #    4502085
 NCBI GeneID    279
 NCBI Accession #    NP_000690.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000699.3 [Other Products]
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 UniProt Primary Accession #    P04746 [Other Products]
 UniProt Secondary Accession #    Q9UBH3; B9EJG1 [Other Products]
 UniProt Related Accession #    P04746 [Other Products]
 Molecular Weight    30,302 Da [Similar Products]
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 NCBI Official Full Name    pancreatic alpha-amylase
 NCBI Official Synonym Full Names    amylase, alpha 2A (pancreatic)
 NCBI Official Symbol    AMY2A [Similar Products]
 NCBI Official Synonym Symbols   
PA; AMY2
[Similar Products]
 NCBI Protein Information    pancreatic alpha-amylase; 1,4-alpha-D-glucan glucanohydrolase; glycogenase; pancreatic amylase alpha 2A
 UniProt Protein Name    Pancreatic alpha-amylase
 UniProt Synonym Protein Names   
1,4-alpha-D-glucan glucanohydrolase
 UniProt Gene Name    AMY2A [Similar Products]
 UniProt Synonym Gene Names    PA [Similar Products]
 UniProt Entry Name    AMYP_HUMAN
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 NCBI Summary for AMY2A    This gene encodes a member of the alpha-amylase family of proteins. Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, catalyzing the first step in digestion of dietary starch and glycogen. This gene and several family members are present in a gene cluster on chromosome 1. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jan 2015]
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 UniProt Comments for AMY2A    AMY2A: Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jul 2008]

Protein type: Carbohydrate Metabolism - starch and sucrose; EC 3.2.1.1; Hydrolase; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p21

Cellular Component: extracellular space; extracellular region

Molecular Function: alpha-amylase activity; calcium ion binding; chloride ion binding

Biological Process: polysaccharide digestion; carbohydrate catabolic process; carbohydrate metabolic process; pathogenesis
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 Research Articles on AMY2A    1. Mammalian pancreatic alpha-amylases share a common carbohydrate binding activity and specifically bind to the intestinal brush border.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-AMY2A antibodyDiseases associated with anti-AMY2A antibody
 Products by Pathway  Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Digestion Of Dietary Carbohydrate Pathway antibodies  Digestion Of Dietary Carbohydrate Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Myoclonic Epilepsy Of Lafora Pathway antibodies  Myoclonic Epilepsy Of Lafora Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >3 publications with AMY2A and Lung Neoplasms
 Diabetes Mellitus Antibodies  >2 publications with AMY2A and Diabetes Mellitus
 Inflammation Antibodies  >2 publications with AMY2A and Inflammation
 Congenital Abnormalities Antibodies  >1 publications with AMY2A and Congenital Abnormalities
 Fatty Liver Antibodies  >1 publications with AMY2A and Fatty Liver
Organs/Tissues associated with anti-AMY2A antibody
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >6 publications with AMY2A and Pancreas
 Bladder Antibodies  >1 publications with AMY2A and Bladder
 Salivary Gland Antibodies  >1 publications with AMY2A and Salivary Gland
 Liver Antibodies  >1 publications with AMY2A and Liver
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