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anti-ANGPTL3 antibody :: Mouse anti-Human, Mouse ANGPTL3 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS200016
Western Blot (WB)
Unit / Price
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 Product Name   

ANGPTL3, Monoclonal Antibody

★Popular Item★
 Also Known As   

ANGPTL3 antibody (clone 1D10)

 Product Synonym Names    angiopoietin-like 3 precusor; ANGPT5; angiopoietin5; angiopoietin-like 3
 Product Gene Name   

anti-ANGPTL3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG1, k
 Clone Number    1D10
 Host    Mouse
 Species Reactivity    Human, Mouse
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 Purity/Purification    By protein-G affinity chromatography
 Form/Format    Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
 Concentration    1mg/ml (lot specific)
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 Antigen Species    Human
 Clone    Anti-human ANGPTL3 mAb, clone 1D10, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ANGPTL3 (243-460aa) protein.
 Immunogen    Recombinant human ANGPTL3 (243-460aa) purified from E Coli
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 Preparation and Storage    Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
 Other Notes    Small volumes of anti-ANGPTL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ANGPTL3 antibody

   Angiopoietin-like 3 (ANGPTL3 or ANGPT5), a liver specific protein, is a secreted factor consisting of an N-terminal coiled-coil domain and C-terminal fibrinogen-like domain. ANGPTL3 is structurally similar to angiopoietins, which are vascular endothelial growth factors. ANGTPLs (ANGTPL3, ANGPTL4 and ANGPTL6) have a major impact on lipid and possibly glucose metabolism. These proteins also have important effects on plasma triacylglycerol clearance, adipose tissue lipolysis, and adiposity.
 Product Categories/Family for anti-ANGPTL3 antibody    Hormones & Cytokines
 Applications Tested/Suitable for anti-ANGPTL3 antibody   

ELISA (EIA), Western Blot (WB) (Cell lysate)

 Application Notes for anti-ANGPTL3 antibody    The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.
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 Western Blot (WB) of anti-ANGPTL3 antibody    The extracts of mouse liver tissue (80ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human ANGPTL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Arrows indicate ANGPTL3 proteins. Upper is a full-length protein(about 63 kDa) and lower is a cleaved form of ANGPTL3 proteins (about 35 kDa) (Ono M. et al., 2003).
anti-ANGPTL3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ANGPTL3. It may not necessarily be applicable to this product.
 NCBI GI #    7656888
 NCBI GeneID    27329
 NCBI Accession #    NP_055310 [Other Products]
 NCBI GenBank Nucleotide #    NM_014495.3 [Other Products]
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 UniProt Secondary Accession #    A0JLS0; B1ALJ0; B2RCW1 [Other Products]
 UniProt Related Accession #    Q9Y5C1 [Other Products]
 Molecular Weight    53,637 Da
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 NCBI Official Full Name    angiopoietin-related protein 3 preproprotein
 NCBI Official Synonym Full Names    angiopoietin-like 3
 NCBI Official Symbol    ANGPTL3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    angiopoietin-related protein 3; angiopoietin 5
 UniProt Protein Name    Angiopoietin-related protein 3
 UniProt Synonym Protein Names   
Angiopoietin-5; ANG-5; Angiopoietin-like protein 3
 Protein Family    Angiopoietin-related protein
 UniProt Gene Name    ANGPTL3 [Similar Products]
 UniProt Synonym Gene Names    ANGPT5; ANG-5 [Similar Products]
 UniProt Entry Name    ANGL3_HUMAN
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Product References and Citations for anti-ANGPTL3 antibody

   Ono M., et al. (2003) J. Biol. Chem. 278, 41804-41809 Inaba T., et al. (2003) J. Biol. Chem. 278, 21344-21351 koishi R., et al. (2002) Nat. Genet. 30, 151-157 kersten S. (2005) Biochem Soc. Trans. 33, 1059-1062
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ANGPTL3 antibodyPathways associated with anti-ANGPTL3 antibody
 Reference Product  PubMed Publications
 LPL antibody  >39 publications with ANGPTL3 and LPL
 APOA5 antibody  >10 publications with ANGPTL3 and APOA5
 GPIHBP1 antibody  >6 publications with ANGPTL3 and GPIHBP1
 TIE1 antibody  >3 publications with ANGPTL3 and TIE1
 Products by Pathway  Pathway Diagram
 Integrins In Angiogenesis Pathway antibodies  Integrins In Angiogenesis Pathway Diagram
Diseases associated with anti-ANGPTL3 antibodyOrgans/Tissues associated with anti-ANGPTL3 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >24 publications with ANGPTL3 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >20 publications with ANGPTL3 and Atherosclerosis
 Fatty Liver Antibodies  >20 publications with ANGPTL3 and Fatty Liver
 Liver Diseases Antibodies  >13 publications with ANGPTL3 and Liver Diseases
 Disease Models, Animal Antibodies  >6 publications with ANGPTL3 and Disease Models, Animal
 Liver Neoplasms Antibodies  >4 publications with ANGPTL3 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with ANGPTL3 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >4 publications with ANGPTL3 and Kidney Diseases
 Inflammation Antibodies  >3 publications with ANGPTL3 and Inflammation
 Renal Insufficiency Antibodies  >3 publications with ANGPTL3 and Renal Insufficiency
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >64 publications with ANGPTL3 and Liver
 Muscle Antibodies  >8 publications with ANGPTL3 and Muscle
 Kidney Antibodies  >8 publications with ANGPTL3 and Kidney
 Brain Antibodies  >4 publications with ANGPTL3 and Brain
 Lung Antibodies  >3 publications with ANGPTL3 and Lung
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