NP_001148
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
51,242 Da
NCBI Official Full Name
annexin A11 isoform 1
NCBI Official Synonym Full Names
annexin A11
NCBI Official Synonym Symbols
NCBI Protein Information
annexin A11
UniProt Protein Name
Annexin A11
UniProt Synonym Protein Names
56 kDa autoantigen; Annexin XI; Annexin-11; Calcyclin-associated annexin 50; CAP-50
UniProt Synonym Gene Names
UniProt Entry Name
ANX11_HUMAN
NCBI Summary for ANXA11
This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, May 2013]
UniProt Comments for ANXA11
ANXA11: a calcium/phospholipid-binding protein found throughout the nucleoplasm at interphase and at the mitotic phase is concentrated at the loop-like structure around the mitotic apparatus. May interact with calcyclin (S100A6) in vivo. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Calcium-binding; Nuclear envelope; Lipid-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 10q23
Cellular Component: nucleoplasm; specific granule; azurophil granule; membrane; cytoplasm; melanosome; spindle; nuclear envelope; midbody; phagocytic vesicle
Molecular Function: protein binding; phosphatidylethanolamine binding; calcium-dependent phospholipid binding; calcium ion binding; calcium-dependent protein binding
Biological Process: response to calcium ion; phagocytosis
Research Articles on ANXA11
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Products associated with anti-ANXA11 antibody
Diseases associated with anti-ANXA11 antibody
Organs/Tissues associated with anti-ANXA11 antibody
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