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anti-ARID3A antibody :: Mouse anti-Human ARID3A Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120057
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARID3A, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human ARID3A

 Product Synonym Names    AT rich interactive domain 3A (BRIGHT- like); BRIGHT; E2FBP1; DRIL3
 Product Gene Name   

anti-ARID3A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    603265
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    ARIDE9C11
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-ARID3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ARID3A antibody

   This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-ARID3A antibody   

Dot Blot (DB), Western Blot (WB)

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 Quality Control of anti-ARID3A antibody    Western blot analysis of immunized recombinant protein, using anti-ARID3A monoclonal antibody.
anti-ARID3A antibody Quality Control image
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 Quality Control #2 of anti-ARID3A antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-ARID3A antibody Quality Control #2 image
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 Western Blot (WB) of anti-ARID3A antibody    Detection of human ARID3A by Western blot.

Samples: Whole cell lysate (25 ug) from HEK293 cells. [Lot No. ARIDE9C11-2]

Predicted molecular weight: 62 kDa
anti-ARID3A antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for ARID3A. It may not necessarily be applicable to this product.
 NCBI GI #    38173799
 NCBI GeneID    1820
 NCBI Accession #    BC060828 [Other Products]
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 UniProt Secondary Accession #    Q5I858; Q6P9C6; Q8IZA7; Q8N4Z3 [Other Products]
 UniProt Related Accession #    Q99856 [Other Products]
 Molecular Weight    62,889 Da
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 NCBI Official Full Name    Homo sapiens AT rich interactive domain 3A (BRIGHT-like), mRNA
 NCBI Official Synonym Full Names    AT rich interactive domain 3A (BRIGHT-like)
 NCBI Official Symbol    ARID3A [Similar Products]
 NCBI Official Synonym Symbols   
DRIL1; DRIL3; BRIGHT; E2FBP1
[Similar Products]
 NCBI Protein Information    AT-rich interactive domain-containing protein 3A; ARID domain-containing 3A; ARID domain-containing protein 3A; AT rich interactive domain 3A (BRIGHT- like) protein; B-cell regulator of IgH transcription; E2F-binding protein 1; dead ringer-like 1; dead ringer-like protein 1
 UniProt Protein Name    AT-rich interactive domain-containing protein 3A
 UniProt Synonym Protein Names   
B-cell regulator of IgH transcription; Bright; Dead ringer-like protein 1; E2F-binding protein 1
 Protein Family    AT-rich interactive domain-containing protein
 UniProt Gene Name    ARID3A [Similar Products]
 UniProt Entry Name    ARI3A_HUMAN
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 NCBI Summary for ARID3A    This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ARID3A    Bright: a member of the ARID (AT-rich interaction domain) family of transcription factors. It was found by its homology to the Drosophila dead ringer protein, which is important for normal embryogenesis. Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription. Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association. This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu. Activates E mu-driven transcription by binding these sites. Contributes to localized control of accessibility and therefore nonrandom gene use during V(D)J recombination.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleolus; lipid raft

Molecular Function: protein binding; protein homodimerization activity; chromatin binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
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 Research Articles on ARID3A    1. Systemic lupus erythematosus (SLE) patients had increased ARID3a+ B cells compared to healthy controls. ARID3a was not expressed in naive B cells of controls, but was abundant in SLE patients. Number of ARID3a+ B cells correlated with disease activity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ARID3A antibodyPathways associated with anti-ARID3A antibody
 Reference Product  PubMed Publications
 BTK antibody  >6 publications with ARID3A and BTK
 PML antibody  >4 publications with ARID3A and PML
 SP100 antibody  >1 publications with ARID3A and SP100
 SUMO1 antibody  >1 publications with ARID3A and SUMO1
 SP140 antibody  >1 publications with ARID3A and SP140
 TP53 antibody  >1 publications with ARID3A and TP53
 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
Diseases associated with anti-ARID3A antibodyOrgans/Tissues associated with anti-ARID3A antibody
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >1 publications with ARID3A and Fibrosis
 Translocation, Genetic Antibodies  >1 publications with ARID3A and Translocation, Genetic
 Brain Diseases Antibodies  >1 publications with ARID3A and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with ARID3A and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4 publications with ARID3A and Bone
 Liver Antibodies  >2 publications with ARID3A and Liver
 Lymph Node Antibodies  >2 publications with ARID3A and Lymph Node
 Embryonic Tissue Antibodies  >2 publications with ARID3A and Embryonic Tissue
 Ovary Antibodies  >1 publications with ARID3A and Ovary
 Kidney Antibodies  >1 publications with ARID3A and Kidney
 Placenta Antibodies  >1 publications with ARID3A and Placenta
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