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Mouse anti-Human Abeta Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS520722 anti-Abeta antibody
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Abeta, Monoclonal Antibody

 Also Known As   

Anti-Human Abeta (aa 17-24), HRPO (clone: 3B7) (Mouse IgG1)

 Product Synonym Names    Anti-Human Abeta (aa 17-24) Monoclonal Antibody
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    3B7
 Host    Mouse
 Species Reactivity    Human
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 Specificity    Human Abeta (aa 17-25)
 Form/Format    HRPO conjugated IgG buffered in PBS with 40% glycerol (v/v) and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. No NaN3 with other preservatives.
 Concentration    0.1 mg/ml (lot specific)
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 Hybridoma Production: Fusion Partner    Sp2/0
 Hybridoma Production: Immunization    Immunogen: (Iso-L-Asp)-DSGY-EVHHQ-KLVFF-AEDVG-SNKGA-Cys (Abeta 7-30) Donor: Balb/c spleen
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 Preparation and Storage    For all formats, store at 4 degree C. For long term storage (Purified, Biotin, HRPO), aliquot and freeze unused portion at - 20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-Abeta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-Abeta antibody

   Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. It is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intra-neuronal neurofibrillary tangles, extracellular amyloid plaques and vascular amyloid deposits. The major constituent of these plaques are aggregates of the neurotoxic amyloid-beta (Abeta or Abeta) peptide. This 36-43 amino acid peptide is derived proteolytically from the transmembrane amyloid precursor protein (APP) by sequential secretase processing.

Although the normal function of Abeta is not well understood, several potential activities have been discovered including activation of kinase enzymes, protection against oxidative stress, regulation of cholesterol transport, and anti-microbial activity (potentially associated with Abeta's pro inflammatory activity).
 Product Categories/Family for anti-Abeta antibody    Human
 Applications Tested/Suitable for anti-Abeta antibody   

ELISA (EIA)

 Application Notes for anti-Abeta antibody    This antibody is suitable for use in ELISA (recommended dilution: 1:64K - 1:128K). This antibody has not been tested in other applications.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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