View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Mouse Acetylated Lysine Monoclonal Antibody Catalog # MBS800631 Unit / Price 0.1 mg / $530 +1 FREE 8GB USB 5x0.1 mg / $2,140 +2 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Acetylated Lysine, Monoclonal Antibody Full Product Name Acetylated Lysine Antibody: RPE Product Synonym Names acetyl lysine antibody; Lysine antibody Matching Pairs Unconjugated Antibody: Acetylated Lysine Clone #7F8 (MBS801115)RPE Conjugated Antibody: Acetylated Lysine Clone #7F8 (MBS800631) Matching Pairs Unconjugated Antibody: Acetylated Lysine Clone #7F8 (MBS802881)RPE Conjugated Antibody: Acetylated Lysine Clone #7F8 (MBS800631) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG1 Clone Number 7F8 Host Mouse Species Reactivity Bovine, Avian Form/Format Protein G Purified Concentration 1mg/mL (lot specific) Conjugate RPE Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide Preparation and Storage -20 degree C Other Notes Small volumes of anti-Acetylated Lysine antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-Acetylated Lysine antibody Background Info: Detects proteins containing acetylated lysine residues in ELISA and WBs. Does not detect non-acetylated lysine residues.Scientific Background: Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine Nepsilon development (5). Product Categories/Family for anti-Acetylated Lysine antibody Cell Signaling; Phosphorylation Applications Tested/Suitable for anti-Acetylated Lysine antibody Western Blot (WB), ELISA (EIA), binds Protein-G, Immunohistochemistry (IHC), Immunofluorescence (IF) Immunohistochemistry (IHC) of anti-Acetylated Lysine antibody Immunohistochemistry analysis using Mouse Anti-Acetylated Lysine Monoclonal Antibody, Clone 7F8. Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Acetylated Lysine Monoclonal Antibody at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Backskin obtained from transgenic mice. Western Blot (WB) of anti-Acetylated Lysine antibody Western Blot analysis of acetylated lysine showing detection of Acetylated Lysine protein using Mouse Anti-Acetylated Lysine Monoclonal Antibody, Clone 7F8. Primary Antibody: Mouse Anti-Acetylated Lysine Monoclonal Antibody at 1:1000. (1) acetylated BSA (75ng of protein), (2) non-acetylated BSA, and (3) marker. TOP Product References and Citations for anti-Acetylated Lysine antibody 1. Yang XJ. (2005). Oncogene. 24:1653-1662. 2. Hassig, C.A. and Schreiber, S.L. (1997). Curr. Opin. Chem. Biol. 1(3): 300-308. 3. Yang XJ. (2004). Bioessays 26:1076-1087. 4. Hughes, R.E. (2002). Curr. Biol. 12: R141-R143. 5. Vigushin, D.M. and Coombes, R.C. (2004). Curr. Cancer Drug Targets 4: 205-218. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP