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Product Name
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Actin, Muscle Speci?c (LOC100533357), Monoclonal Antibody
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Also Known As
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Actin, Muscle Speci?c (BSA & Azide Free)
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Product Synonym Names
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Anti -Actin, Muscle Speci c (BSA & Azide Free)
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Product Gene Name
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[Similar Products]
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Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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TOP
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Chromosome Location
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chromosome: Un
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3D Structure
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ModBase 3D Structure for P17304
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Clonality
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Monoclonal
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Isotype
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IgG1,k
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Clone Number
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3F10
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Host
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Mouse
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Species Reactivity
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Bovine, Canine, Equine, Human, Mouse, Porcine, Rat
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Specificity
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Recognizes alpha-smooth muscle as well as alpha-skeletal and alpha-cardiac (sarcomeric) isoforms of human actin. Reacts with tumors arising from smooth muscle (leiomyosarcomas) as well as skeletal muscle (rhabdomyosarcomas). Species Crossreactivity: mouse, rat, porcine, equine, bovine, canine.
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Purity/Purification
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Affinity Purified Purified by Protein G affinity chromatography.
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Form/Format
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Supplied as a liquid in PBS, pH 7.4. Also available with BSA and azide. See A0760-22A.
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Immunogen
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Purified actin
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Positive Control
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Muscle or sarcoma
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Preparation and Storage
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May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Other Notes
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Small volumes of anti-LOC100533357 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Categories/Family for anti-LOC100533357 antibody
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Antibodies; Abs to Actin Related Proteins
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Applications Tested/Suitable for anti-LOC100533357 antibody
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Immunohistochemistry (IHC), Immunofluorescence (IF)
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Application Notes for anti-LOC100533357 antibody
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Suitable for use in Immunofluorescence and Immunohistochemistry. Dilution: Immunohistochemistry (Formalin and paraffin): 1-2ug/ml for 30 minutes at RT. No special pretreatment is required for immunohistochemical staining of formalin-fixed tissues.
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NCBI/Uniprot data below describe general gene information for LOC100533357. It may not necessarily be applicable to this product. |
NCBI GI #
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325297142
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NCBI GeneID
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100533357
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NCBI Accession #
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NP_001191580.1
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[Other Products]
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NCBI GenBank Nucleotide #
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NM_001204651.1
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[Other Products]
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UniProt Primary Accession #
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P17304
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[Other Products]
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UniProt Related Accession #
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P17304
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[Other Products]
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Molecular Weight
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41,766 Da
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[Similar Products]
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TOP
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NCBI Official Full Name
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actin, muscle
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NCBI Official Symbol
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LOC100533357
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[Similar Products]
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NCBI Protein Information
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actin, muscle
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UniProt Protein Name
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Actin, muscle
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UniProt Entry Name
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ACTM_APLCA
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UniProt Comments for LOC100533357
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Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
Subunit structure: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
Subcellular location: Cytoplasm › cytoskeleton.
Tissue specificity: Expressed in the muscular cells of the sheath surrounding abdominal ganglions.
Sequence similarities: Belongs to the actin family.
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Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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