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anti-ACOT11 antibody :: Mouse Acyl-Coenzyme A Thioesterase 11 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS140211 anti-ACOT11 antibody
Unit / Price
0.005 mg  /  $140 +1 FREE 8GB USB
0.02 mg  /  $205 +1 FREE 8GB USB
0.1 mg  /  $505 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Acyl-Coenzyme A Thioesterase 11 (ACOT11), Monoclonal Antibody

 Also Known As   

Mouse Anti Human Acyl-Coenzyme A Thioesterase 11

 Product Synonym Names    ACOT11 Antibody; Acyl-Coenzyme A Thioesterase 11, Mouse Anti Human; Acyl-coenzyme A thioesterase 11; Acyl-CoA thioesterase 11; Acyl-CoA thioester hydrolase 11; Brown fat-inducible thioesterase; BFIT; Adipose-associated thioesterase; ACOT11; BFIT; KIAA0707; THEA; BFIT1; BFIT2; THEM1; STARD14
 Product Gene Name   

anti-ACOT11 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606803
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 Clonality    Monoclonal
 Isotype    IgG2b heavy chain and kappa light chain
 Clone Number    PJ4B2AT
 Host    Mouse
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 Purity/Purification    ACOT11 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
 Form/Format    1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
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 Immunogen    Anti-human ACOT11 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACOT11 amino acids 19-250 purified from E Coli.
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 Preparation and Storage    For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
 Other Notes    Small volumes of anti-ACOT11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ACOT11 antibody

   Introduction: ACOT11 is a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse ACOT11 has been linked to obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice.
 Product Categories/Family for anti-ACOT11 antibody    MONOCLONAL ANTIBODIES, ANTI-HUMAN ENZYMES; Monoclonal Antibodies; Anti Human Enzyme
 Applications Tested/Suitable for anti-ACOT11 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ACOT11 antibody    ACOT11 antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500 ~ 1:2,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:100.
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NCBI/Uniprot data below describe general gene information for ACOT11. It may not necessarily be applicable to this product.
 NCBI GI #    22165355
 NCBI GeneID    26027
 NCBI Accession #    NP_056362.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_015547.3 [Other Products]
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 UniProt Secondary Accession #    O75187; Q52LP1; Q53ER9; Q96DI1; Q9H883; B1AQ22; D3DQ50 [Other Products]
 UniProt Related Accession #    Q8WXI4 [Other Products]
 Molecular Weight    67,152 Da
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 NCBI Official Full Name    acyl-coenzyme A thioesterase 11 isoform 1
 NCBI Official Synonym Full Names    acyl-CoA thioesterase 11
 NCBI Official Symbol    ACOT11 [Similar Products]
 NCBI Official Synonym Symbols   
BFIT; THEA; THEM1; STARD14
[Similar Products]
 NCBI Protein Information    acyl-coenzyme A thioesterase 11; START domain containing 14; StAR-related lipid transfer (START) domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase superfamily member 1; thioesterase, adipose associated
 UniProt Protein Name    Acyl-coenzyme A thioesterase 11
 UniProt Synonym Protein Names   
Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; BFIT
 Protein Family    Acyl-coenzyme A thioesterase
 UniProt Gene Name    ACOT11 [Similar Products]
 UniProt Synonym Gene Names    BFIT; KIAA0707; THEA; Acyl-CoA thioesterase 11; BFIT [Similar Products]
 UniProt Entry Name    ACO11_HUMAN
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 NCBI Summary for ACOT11    This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
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 UniProt Comments for ACOT11    ACOT11: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.1.2.-

Chromosomal Location of Human Ortholog: 1p32.3

Cellular Component: cytoplasm

Molecular Function: acyl-CoA hydrolase activity; lipid binding

Biological Process: response to temperature stimulus; response to cold; fatty acid metabolic process
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 Research Articles on ACOT11    1. The N-terminal region of human fat inducible thioesterase variant 2 constitutes a mitochondrial location signal sequence, which undergoes mitochondrion-dependent posttranslational cleavage.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-ACOT11 antibodyOrgans/Tissues associated with anti-ACOT11 antibody
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >1 publications with ACOT11 and Insulin Resistance
 Fatty Liver Antibodies  >1 publications with ACOT11 and Fatty Liver
 Inflammation Antibodies  >1 publications with ACOT11 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >4 publications with ACOT11 and Adipose Tissue
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