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anti-ACE antibody :: Angiotensin I Converting Enzyme-1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS601134 anti-ACE antibody
Unit / Price
0.1 mL  /  $685 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Angiotensin I Converting Enzyme-1 (ACE), Monoclonal Antibody

 Also Known As   

Anti - Angiotensin I Converting Enzyme-1 (ACE-1)

 Product Synonym Names    Angiotensin I Converting Enzyme-1 (ACE-1)
 Product Gene Name   

anti-ACE antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 17; NC_000017.10 (61554434..61575741). Location: 17q23.3
 OMIM    106180
 3D Structure    ModBase 3D Structure for P12821
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 Clonality    Monoclonal
 Isotype    IgG
 Clone Number    9j105
 Host    Host: Mouse
Source: Rat
 Species Reactivity    Feline, Hamster, Human, Rat
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 Specificity    Recognizes rat Angiotensin I Converting Enzyme-1. Does not crossreact with ACE-2. Species Crossreactivity: mouse, human, hamster, feline.
 Purity/Purification    Purified by Protein A/G column.
 Form/Format    Affinity Purified
Supplied as a liquid in PBS, 0.1% sodium azide, 40% glycerol.
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 Immunogen    Purified human/rat lung ACE protein.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-ACE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-ACE antibody

   Renin-Angiotensin System (RAS) is a critical regulator of blood pressure homeostasis. The protease renin cleaves angiotensinogen into inactive decameric peptide angiotensin-I
 Product Categories/Family for anti-ACE antibody    Abs to Enzymes
 Applications Tested/Suitable for anti-ACE antibody   

ELISA, Western Blot

 Application Notes for anti-ACE antibody    Suitable for use in ELISA and Western Blot. Other applications not tested.
Dilution: ELISA: 1:1000-1:10,000
Western Blot: 2-5ug/ml
Optimal dilutions to be determined by the researcher.
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NCBI/Uniprot data below describe general gene information for ACE. It may not necessarily be applicable to this product.
 NCBI GI #    4503273
 NCBI GeneID    1636
 NCBI Accession #    NP_000780.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000789.3 [Other Products]
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 UniProt Primary Accession #    P12821 [Other Products]
 UniProt Secondary Accession #    P22966; Q53YX9; Q59GY8; Q7M4L4; B0LPF0 [Other Products]
 UniProt Related Accession #    P12821; Q16425; Q3KRI5 [Other Products]
 Molecular Weight    149,715 Da [Similar Products]
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 NCBI Official Full Name    angiotensin-converting enzyme isoform 1
 NCBI Official Synonym Full Names    angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
 NCBI Official Symbol    ACE [Similar Products]
 NCBI Official Synonym Symbols   
DCP; ACE1; DCP1; CD143; MVCD3; MGC26566
[Similar Products]
 NCBI Protein Information    angiotensin-converting enzyme; kininase II; peptidase P; CD143 antigen; testicular ECA; carboxycathepsin; OTTHUMP00000206956; dipeptidyl carboxypeptidase 1; dipeptidyl carboxypeptidase I; angiotensin converting enzyme, somatic isoform
 UniProt Protein Name    Angiotensin-converting enzyme
 UniProt Synonym Protein Names   
Dipeptidyl carboxypeptidase I; Kininase II
 Protein Family    Acetylcholinesterase
 UniProt Gene Name    ACE [Similar Products]
 UniProt Synonym Gene Names    DCP; DCP1 [Similar Products]
 UniProt Entry Name    ACE_HUMAN
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Product References and Citations for anti-ACE antibody

   • 1. Tipnis, S. R et al (2000) JBC Vol. 275: 33238-33243;
• 2. Crackower, M. A et al (2002), Nature417: 822-828;
• 3. Huang, L et al (2003) JBC Vol. 278: 15532-15540.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Anti - Angiotensin I Converting Enzyme-1 (ACE-1)
 Catalog #  Product Name
 MBS601134  Anti - Angiotensin I Converting Enzyme-1 (ACE-1)
Products associated with anti-ACE antibodyPathways associated with anti-ACE antibody
 Reference Product  PubMed Publications
 AGTR2 antibody  >335 publications with ACE and AGTR2
 BDKRB2 antibody  >293 publications with ACE and BDKRB2
 COMT antibody  >8 publications with ACE and COMT
 Products by Pathway  Pathway Diagram
 ACE Inhibitor Pathway antibodies  ACE Inhibitor Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Hypertrophic Cardiomyopathy (HCM) Pathway antibodies  Hypertrophic Cardiomyopathy (HCM) Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
Diseases associated with anti-ACE antibodyOrgans/Tissues associated with anti-ACE antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >12479 publications with ACE and Cardiovascular Diseases
 Hypertension Antibodies  >8010 publications with ACE and Hypertension
 Heart Failure Antibodies  >4287 publications with ACE and Heart Failure
 Kidney Diseases Antibodies  >3127 publications with ACE and Kidney Diseases
 Myocardial Infarction Antibodies  >2396 publications with ACE and Myocardial Infarction
 Coronary Artery Disease Antibodies  >2009 publications with ACE and Coronary Artery Disease
 Stroke Antibodies  >1254 publications with ACE and Stroke
 Renal Insufficiency Antibodies  >1174 publications with ACE and Renal Insufficiency
 Cardiomegaly Antibodies  >1013 publications with ACE and Cardiomegaly
 Diabetes Mellitus, Type 2 Antibodies  >936 publications with ACE and Diabetes Mellitus, Type 2
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >10915 publications with ACE and Blood
 Heart Antibodies  >7428 publications with ACE and Heart
 Vascular Antibodies  >4170 publications with ACE and Vascular
 Kidney Antibodies  >3671 publications with ACE and Kidney
 Muscle Antibodies  >1985 publications with ACE and Muscle
 Lung Antibodies  >1413 publications with ACE and Lung
 Brain Antibodies  >1104 publications with ACE and Brain
 Intestine Antibodies  >241 publications with ACE and Intestine
 Testis Antibodies  >216 publications with ACE and Testis
 Eye Antibodies  >200 publications with ACE and Eye
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