NP_001025444.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform b
NCBI Official Synonym Full Names
aryl hydrocarbon receptor nuclear translocator-like
NCBI Official Synonym Symbols
TIC; JAP3; MOP3; BMAL1; PASD3; BMAL1c; bHLHe5; MGC47515 [Similar Products]
NCBI Protein Information
aryl hydrocarbon receptor nuclear translocator-like protein 1; OTTHUMP00000197997; OTTHUMP00000197998; OTTHUMP00000197999; OTTHUMP00000198000; OTTHUMP00000198001; bHLH-PAS protein JAP3; member of PAS protein 3; member of PAS superfamily 3; brain and muscle ARNT-like 1; PAS domain-containing protein 3; ARNT-like protein 1, brain and muscle; basic-helix-loop-helix-PAS orphan MOP3; basic-helix-loop-helix-PAS protein MOP3; class E basic helix-loop-helix protein 5
UniProt Protein Name
Aryl hydrocarbon receptor nuclear translocator-like protein 1
UniProt Synonym Protein Names
Basic-helix-loop-helix-PAS protein MOP3; Brain and muscle ARNT-like 1; Class E basic helix-loop-helix protein 5; bHLHe5; Member of PAS protein 3; PAS domain-containing protein 3; bHLH-PAS protein JAP3
UniProt Synonym Gene Names
UniProt Entry Name
BMAL1_HUMAN
NCBI Summary for ARNTL
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
UniProt Comments for ARNTL
BMAL1: aryl hydrocarbon receptor nuclear translocator-like protein. A circadian regulatory protein and substrate of casein kinase I epsilon. Heterodimers bind to an E-box element (3'-CACGTG-5'), thereby activating transcription of PER1, and possibly of other circadian clock proteins. Seven splice isoforms have been reported.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 11p15
Cellular Component: transcription factor complex; PML body; nucleus
Molecular Function: signal transducer activity; protein binding; DNA binding; aryl hydrocarbon receptor binding; sequence-specific DNA binding; protein heterodimerization activity; bHLH transcription factor binding; Hsp90 protein binding
Biological Process: transcription from RNA polymerase II promoter; circadian rhythm; proteasomal ubiquitin-dependent protein catabolic process; negative regulation of TOR signaling pathway; regulation of cell cycle; positive regulation of transcription, DNA-dependent; response to redox state; positive regulation of circadian rhythm; negative regulation of fat cell differentiation; signal transduction; regulation of neurogenesis; regulation of transcription, DNA-dependent; protein import into nucleus, translocation; spermatogenesis; regulation of protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent; regulation of hair cycle; regulation of insulin secretion
Research Articles on ARNTL
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Products associated with anti-ARNTL antibody
Pathways associated with anti-ARNTL antibody
Diseases associated with anti-ARNTL antibody
Organs/Tissues associated with anti-ARNTL antibody
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