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anti-BAFF antibody :: Mouse anti-Human BAFF Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS690156 anti-BAFF antibody
Unit / Price
0.5 mg  /  $470 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BAFF, Monoclonal Antibody

★Popular Item★
 Also Known As   

Anti-Human BAFF

 Product Synonym Names    Monoclonal antibody anti-human BAFF
 Product Gene Name   

anti-BAFF antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 3; NC_000003.12 (98732236..98795845). Location: 3q12.1
 OMIM    607156
 3D Structure    ModBase 3D Structure for Q9Y274
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 Clonality    Monoclonal
 Isotype    IgG1, kappa
 Host    Mouse
 Species Reactivity    Human
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 Purity/Purification    Protein G chromatography
 Form/Format    Lyophilized
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 Immunogen    highly pure (>98%) recombinant human BAFF
 Antibody Generation    Monoclonal antibodies were produced in BALB/c mice using recombinant human BAFF as the immunizing antigen. This IgG1/K antibody was purified from ascites fluid on a protein A chromatography column.
 Protein RefSeq    NP_006564.1
 Uniprot ID    Q9Y274
 mRNA RefSeq    NM_006573.4
 Buffer    PBS
 Reconstitution buffer    water
 Reconstitution    Centrifuge vial prior to opening. Reconstitute the antibody in sterile water to a concentration of 0.1 - 1.0 mg/ml.
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 Preparation and Storage    Stability: Lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least 2 weeks at 2-8 degree C. Frozen aliquots are stable for at least 6 months when stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-BAFF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BAFF antibody

   BAFF, also known as Blymphocyte stimulator (BLyS), TNFand APO-Lrelated leukocyte expressed ligand 1 (TALL1), and TNF homolog that activates apoptosis, NFKB and JNK (THANK), is a TNF ligand superfamily member and has been designated TNFSF13B.
 Applications Tested/Suitable for anti-BAFF antibody   

ELISA; Western Blot (WB)

 Application Notes for anti-BAFF antibody    ELISA:
In a Sandwich ELISA (assuming 100 ?l/well), a concentration of 5-6 ug/ml of this antibody will detect at least 1000 pg/ml of recombinant Human BAFF when used in conjunction with an appropriate conjugated secondary antibody as detection system.

Western Blot:
To detect hBAFF by Western Blot analysis this antibody can be used at a concentration of 0.25 - 0.50 ug/ml. When used in conjunction with compatible secondary reagents the detection limit for recombinant hBAFF is 1 - 2 ng/lane, under reducing and non-reducing conditions.
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NCBI/Uniprot data below describe general gene information for BAFF. It may not necessarily be applicable to this product.
 NCBI GI #    403225032
 NCBI GeneID    10402
 NCBI Accession #    NP_001258074.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001271145.1 [Other Products]
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 UniProt Primary Accession #    Q9Y274 [Other Products]
 UniProt Secondary Accession #    B2RCH2; B3KMI1; D3DN39; F8W6U0 [Other Products]
 UniProt Related Accession #    Q9Y274 [Other Products]
 Molecular Weight    38,214 Da
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 NCBI Official Full Name    type 2 lactosamine alpha-2,3-sialyltransferase isoform 3
 NCBI Official Synonym Full Names    ST3 beta-galactoside alpha-2,3-sialyltransferase 6
 NCBI Official Symbol    ST3GAL6 [Similar Products]
 NCBI Official Synonym Symbols   
SIAT10; ST3GALVI
[Similar Products]
 NCBI Protein Information    type 2 lactosamine alpha-2,3-sialyltransferase; alpha2,3-sialyltransferase ST3Gal VI; sialyltransferase 10 (alpha-2,3-sialyltransferase VI); CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI
 UniProt Protein Name    Type 2 lactosamine alpha-2,3-sialyltransferase
 UniProt Synonym Protein Names   
CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; ST3Gal VI; ST3GalVI; Sialyltransferase 10
 UniProt Gene Name    ST3GAL6 [Similar Products]
 UniProt Synonym Gene Names    SIAT10; ST3GalVI [Similar Products]
 UniProt Entry Name    SIA10_HUMAN
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 NCBI Summary for BAFF    The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]
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 UniProt Comments for BAFF    Function: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.

Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein

Potential.

Tissue specificity: Ubiquitous.

Sequence similarities: Belongs to the glycosyltransferase 29 family.
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 Research Articles on BAFF    1. the occurrence of CD75s- and iso-CD75s-gangliosides in tumor tissues is largely independent of the transcriptional expression of ST6GAL1 and ST3GAL6
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BAFF antibodyPathways associated with anti-BAFF antibody
 Reference Product  PubMed Publications
 FUT4 antibody  >2 publications with BAFF and FUT4
 B4GALT1 antibody  >1 publications with BAFF and B4GALT1
 CHST6 antibody  >1 publications with BAFF and CHST6
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Keratan Sulfate Biosynthesis Pathway antibodies  Keratan Sulfate Biosynthesis Pathway Diagram
 Keratan Sulfate/keratin Metabolism Pathway antibodies  Keratan Sulfate/keratin Metabolism Pathway Diagram
 MPS I - Hurler Syndrome Pathway antibodies  MPS I - Hurler Syndrome Pathway Diagram
 MPS II - Hunter Syndrome Pathway antibodies  MPS II - Hunter Syndrome Pathway Diagram
 MPS IIIA - Sanfilippo Syndrome A Pathway antibodies  MPS IIIA - Sanfilippo Syndrome A Pathway Diagram
 MPS IIIB - Sanfilippo Syndrome B Pathway antibodies  MPS IIIB - Sanfilippo Syndrome B Pathway Diagram
Diseases associated with anti-BAFF antibodyOrgans/Tissues associated with anti-BAFF antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with BAFF and Breast Neoplasms
 Intestinal Diseases Antibodies  >1 publications with BAFF and Intestinal Diseases
 Depressive Disorder Antibodies  >1 publications with BAFF and Depressive Disorder
 Fibrosis Antibodies  >1 publications with BAFF and Fibrosis
 Carcinoma, Hepatocellular Antibodies  >1 publications with BAFF and Carcinoma, Hepatocellular
 Inflammation Antibodies  >1 publications with BAFF and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with BAFF and Blood
 Bone Antibodies  >1 publications with BAFF and Bone
 Muscle Antibodies  >1 publications with BAFF and Muscle
 Vascular Antibodies  >1 publications with BAFF and Vascular
 Intestine Antibodies  >1 publications with BAFF and Intestine
 Liver Antibodies  >1 publications with BAFF and Liver
 Heart Antibodies  >1 publications with BAFF and Heart
 Lung Antibodies  >1 publications with BAFF and Lung
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