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anti-BRRN1 antibody :: Mouse anti-Human BRRN1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120479
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BRRN1, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human BRRN1

 Product Synonym Names    Homo sapiens non-SMC condensin I complex, subunit H (NCAPH), mRNA.; BRRN1; CAP-H; HCAP-H
 Product Gene Name   

anti-BRRN1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602332
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    2094C4_2a
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-BRRN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-BRRN1 antibody

   This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. [provided by RefSeq][NCBI Entrez Gene Summary]
 Applications Tested/Suitable for anti-BRRN1 antibody   

Dot Blot (DB)

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 Quality Control of anti-BRRN1 antibody    Western blot analysis of immunized recombinant protein, using anti-BRRN1 monoclonal antibody.
anti-BRRN1 antibody Quality Control image
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 Quality Control #2 of anti-BRRN1 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-BRRN1 antibody Quality Control #2 image
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NCBI/Uniprot data below describe general gene information for BRRN1. It may not necessarily be applicable to this product.
 NCBI GI #    528281398
 NCBI GeneID    23397
 NCBI Accession #    NP_056156.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_015341 [Other Products]
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 UniProt Secondary Accession #    Q8TB87; B4E189 [Other Products]
 UniProt Related Accession #    Q15003 [Other Products]
 Molecular Weight    67,495 Da
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 NCBI Official Full Name    Homo sapiens non-SMC condensin I complex, subunit H (NCAPH), transcript variant 1, mRNA
 NCBI Official Synonym Full Names    non-SMC condensin I complex, subunit H
 NCBI Official Symbol    NCAPH [Similar Products]
 NCBI Official Synonym Symbols   
BRRN1; CAP-H
[Similar Products]
 NCBI Protein Information    condensin complex subunit 2; barren homolog 1; chromosome-associated protein H
 UniProt Protein Name    Condensin complex subunit 2
 UniProt Synonym Protein Names   
Barren homolog protein 1; Chromosome-associated protein H; hCAP-H; Non-SMC condensin I complex subunit H; XCAP-H homolog
 UniProt Gene Name    NCAPH [Similar Products]
 UniProt Entry Name    CND2_HUMAN
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 NCBI Summary for BRRN1    This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]
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 UniProt Comments for BRRN1    NCAPH: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Belongs to the CND2 (condensin subunit 2) family.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: membrane; cytoplasm; condensin complex; nucleus; cytosol

Molecular Function: protein binding

Biological Process: cell division; mitotic chromosome condensation; mitotic cell cycle
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 Research Articles on BRRN1    1. Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell death.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BRRN1 antibodyPathways associated with anti-BRRN1 antibody
 Reference Product  PubMed Publications
 SMC2 antibody  >11 publications with BRRN1 and SMC2
 NCAPG antibody  >2 publications with BRRN1 and NCAPG
 NUSAP1 antibody  >1 publications with BRRN1 and NUSAP1
 NCAPD2 antibody  >1 publications with BRRN1 and NCAPD2
 AURKB antibody  >1 publications with BRRN1 and AURKB
 Products by Pathway  Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Condensation Of Prometaphase Chromosomes Pathway antibodies  Condensation Of Prometaphase Chromosomes Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 Mitotic Prometaphase Pathway antibodies  Mitotic Prometaphase Pathway Diagram
Organs/Tissues associated with anti-BRRN1 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with BRRN1 and Muscle
 Liver Antibodies  >1 publications with BRRN1 and Liver
 Brain Antibodies  >1 publications with BRRN1 and Brain
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