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Mouse Bacillus anthracis Protective Antigen Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS190058 anti-Bacillus anthracis Protective Antigen antibody
Unit / Price
0.2 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bacillus anthracis Protective Antigen, Monoclonal Antibody

 Also Known As   

Bacillus anthracis Protective Antigen Monoclonal Antibody

 Product Synonym Names    Bacillus anthracis Protective Antigen; Bacillus anthracis Protective Antigen
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG2b
 Host    Mouse
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 Specificity    Bacillus anthracis Protective Antigen [These monoclonal antibodies recognize different epitopes of the 83kD and 63kD forms of B. anthracis Protective Antigen. They do not cross-react with B. anthracis Edema Factor, Lethal Factor, or spore/vegetative surface antigens.]
These antibodies recognize different epitopes of the 83kD and 63 kD forms of B. anthracis PA. They do not crossreact with B. anthracis EF, LF, or spore/vegetative surface antigens.
 Form/Format    200 ug purified antibody in PBS, pH 7.4.
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 Antigen    Purified B. anthracis Protective Antigen (83 kD).
 Preservatives    0.1% NaN3
 Dilutions Instructions    Dilute in PBS or medium which is identical to that used in the assay system.
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 Preparation and Storage    These antibodies are stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
 Other Notes    Small volumes of anti-Bacillus anthracis Protective Antigen antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-Bacillus anthracis Protective Antigen antibody

   Anthrax toxin produced by Bacillus anthracis is composed of three proteins: Protective Antigen (PA), Edema Factor (EF), and Lethal Factor (LF). Toxicity requires the assembly of all three of these proteins, and this process is initiated when full-length PA binds to the cell surface ATR (anthrax toxin receptor). After binding, PA is enzymatically cleaved to yield a 63 kD fragment which then binds EF and LF, and the complex is internalized.
 Product Categories/Family for anti-Bacillus anthracis Protective Antigen antibody    BioWarfare Antibodies
 Applications Tested/Suitable for anti-Bacillus anthracis Protective Antigen antibody   

ELISA, Immunoblot

 Application Notes for anti-Bacillus anthracis Protective Antigen antibody    Immunoblotting: use 18721, 18723, 18725, or 18726 at 5 ug/ml.
Sandwich ELISA: use coating antibody (18720 or 18725) at 5 ug/ml; use detect antibody (18722, 18723, or18726) at 1 ug/ml.
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NCBI/Uniprot data below describe general gene information for Bacillus anthracis Protective Antigen. It may not necessarily be applicable to this product.
 NCBI GI #    156255913
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 NCBI Official Full Name    Bacillus anthracis protective antigen
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Bacillus anthracis Protective Antigen antibodyPathways associated with anti-Bacillus anthracis Protective Antigen antibody
 Reference Product  PubMed Publications
 FLNA antibody  >12 publications with Bacillus anthracis Protective Antigen and FLNA
 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
Organs/Tissues associated with anti-Bacillus anthracis Protective Antigen antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with Bacillus anthracis Protective Antigen and Bone
 Connective Tissue Antibodies  >4 publications with Bacillus anthracis Protective Antigen and Connective Tissue
 Heart Antibodies  >3 publications with Bacillus anthracis Protective Antigen and Heart
 Muscle Antibodies  >3 publications with Bacillus anthracis Protective Antigen and Muscle
 Brain Antibodies  >3 publications with Bacillus anthracis Protective Antigen and Brain
 Vascular Antibodies  >2 publications with Bacillus anthracis Protective Antigen and Vascular
 Embryonic Tissue Antibodies  >2 publications with Bacillus anthracis Protective Antigen and Embryonic Tissue
 Ear Antibodies  >1 publications with Bacillus anthracis Protective Antigen and Ear
 Kidney Antibodies  >1 publications with Bacillus anthracis Protective Antigen and Kidney
 Umbilical Cord Antibodies  >1 publications with Bacillus anthracis Protective Antigen and Umbilical Cord
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