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anti-CRP antibody :: Mouse anti-Human C Reactive Protein (CRP) Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS313124
Testing Data
Unit / Price
1 mg  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C Reactive Protein (CRP), Monoclonal Antibody

 Also Known As   

MAb to CRP

 Product Synonym Names    Monoclonal Antibody to Human C Reactive Protein (CRP)
 Product Gene Name   

anti-CRP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000001.10 (159682079..159684379, complement). Location: 1q21-q23
 OMIM    123260
 3D Structure    ModBase 3D Structure for P02741
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 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    108-2A2
 Host    Mouse
 Species Reactivity    Human
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 Specificity    C Reactive Protein (CRP) (Human CRP. Recognizes antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.)
 Purity/Purification    > 90% pure (SDS-PAGE). Protein A Chromatography Product is 0.2 um filtered.
 Form/Format    Purified, Liquid
 Concentration    4.79 mg/mL (OD280nm, E0.1% = 1.4) (lot specific)
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 Preservative    0.05% Sodium Azide
 Immunogen    Purified Human CRP
 Affinity Constant    Not Determined
 Buffer    10 mM Sodium Phosphate, 150 mM Sodium Chloride, pH 7.4 + 0.2
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 Preparation and Storage    Short term (up to 7 days) store at 2-8 degree C. Long term, aliquot and store at -20 degree C. Avoid multiple freeze/thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CRP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CRP antibody    Monoclonal Antibodies to Cardiac Markers
 Applications Tested/Suitable for anti-CRP antibody   

ELISA (EIA)

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 Testing Data of anti-CRP antibody    anti-CRP antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
 NCBI GI #    30224
 NCBI GeneID    1401
 NCBI Accession #    CAA39671.1 [Other Products]
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 UniProt Primary Accession #    P02741 [Other Products]
 UniProt Secondary Accession #    Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0 [Other Products]
 UniProt Related Accession #    P02741 [Other Products]
 Molecular Weight    25,039 Da [Similar Products]
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 NCBI Official Full Name    C-reactive protein
 NCBI Official Synonym Full Names    C-reactive protein, pentraxin-related
 NCBI Official Symbol    CRP [Similar Products]
 NCBI Official Synonym Symbols   
PTX1
[Similar Products]
 NCBI Protein Information    C-reactive protein; pentraxin 1
 UniProt Protein Name    C-reactive protein
 Protein Family    Cryparin
 UniProt Gene Name    CRP [Similar Products]
 UniProt Synonym Gene Names    PTX1 [Similar Products]
 UniProt Entry Name    CRP_HUMAN
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 NCBI Summary for CRP    The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
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 UniProt Comments for CRP    Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

Cofactor: Binds 2 calcium ions per subunit.

Subunit structure: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.

Subcellular location: Secreted.

Tissue specificity: Found in plasma.

Induction: The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL1/interleukin-1 and IL6//interleukin-6.

Miscellaneous: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.

Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain.

Mass spectrometry: Molecular mass is 23028 Da from positions 19 - 224. Determined by MALDI. Ref.15Molecular mass is 22930 Da from positions 19 - 223. Determined by MALDI. Ref.15
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 Research Articles on CRP    1. We showed no evidence for a role of hs-CRP, C3 and C4 in the association between BMI and asthma symptoms in overweight children.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRP antibodyPathways associated with anti-CRP antibody
 Reference Product  PubMed Publications
 CFH antibody  >17 publications with CRP and CFH
 FCGR2A antibody  >6 publications with CRP and FCGR2A
 APCS antibody  >6 publications with CRP and APCS
 LEP antibody  >5 publications with CRP and LEP
 FCGR1A antibody  >5 publications with CRP and FCGR1A
 FCGR2B antibody  >4 publications with CRP and FCGR2B
 GP6 antibody  >2 publications with CRP and GP6
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with anti-CRP antibodyOrgans/Tissues associated with anti-CRP antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >8483 publications with CRP and Inflammation
 Cardiovascular Diseases Antibodies  >6718 publications with CRP and Cardiovascular Diseases
 Infection Antibodies  >3532 publications with CRP and Infection
 Heart Diseases Antibodies  >3246 publications with CRP and Heart Diseases
 Myocardial Ischemia Antibodies  >2629 publications with CRP and Myocardial Ischemia
 Coronary Artery Disease Antibodies  >2368 publications with CRP and Coronary Artery Disease
 Necrosis Antibodies  >2345 publications with CRP and Necrosis
 Atherosclerosis Antibodies  >2302 publications with CRP and Atherosclerosis
 Arthritis, Rheumatoid Antibodies  >1598 publications with CRP and Arthritis, Rheumatoid
 Nervous System Diseases Antibodies  >1588 publications with CRP and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14887 publications with CRP and Blood
 Liver Antibodies  >1045 publications with CRP and Liver
 Muscle Antibodies  >938 publications with CRP and Muscle
 Lung Antibodies  >788 publications with CRP and Lung
 Brain Antibodies  >708 publications with CRP and Brain
 Pancreas Antibodies  >112 publications with CRP and Pancreas
 Bladder Antibodies  >43 publications with CRP and Bladder
 Placenta Antibodies  >42 publications with CRP and Placenta
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