Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CAT rightarrow Monoclonal CAT  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Protein Carbonyl (PC) ELISA Kit
 • mitochondrial tumor suppressor 1 (MTUS1) ELISA Kit
 • Staphylococcus aureus Antibody
 • Fibroblast Growth Factor 21 (FGF21) Antibody
 • Inhibin B (INH-B) ELISA Kit
 • Vitamin E (VE) ELISA Kit
 • Acetylcholinesterase (ACHE) ELISA Kit
 • Migration Inhibitory Factor (MIF) Recombinant Protein
 • Mycoplasma sp.Modification methylase MunI (munIM) Recombinant Protein
 • Heme Oxygenase 2, Decycling (HO2) ELISA Kit
 • G Protein Coupled Receptor (GPCR) ELISA Kit
 • Growth Differentiation Factor 1 (GDF1) Recombinant Protein
 • fucokinase (FUK) ELISA Kit
 • Cytokeratin HMW, AE3 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CAT antibody :: Mouse CAT / Catalase Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS245275
Unit / Price
0.05 mL  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CAT / Catalase, Monoclonal Antibody

 Also Known As   

Mouse Monoclonal (IgG2a,k) to Human CAT / Catalase

 Product Synonym Names    Anti-CAT / Catalase Antibody IHC-plus; CAT; Catalase; Human CAT; Catalase
 Product Gene Name   

anti-CAT antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    gene 614097
 3D Structure    ModBase 3D Structure for P04040
Section Bar
 Clonality    Monoclonal
 Isotype    IgG2a,k
 Host    Mouse
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Purified
 Form/Format    HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
 Concentration    1 mg/ml (lot specific)
Section Bar
 Target Species    Human
 Immunogen Description    Recombinant human CAT / Catalase purified from E Coli.
 Immunogen Type    Recombinant protein
 Immunogen    CAT / Catalase antibody was raised against recombinant human CAT / Catalase purified from E Coli.
Section Bar
 Preparation and Storage    +4 degree C or -20 degree C, Avoid repeated freezing and thawing.
 Other Notes    Small volumes of anti-CAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-CAT antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-CAT antibody    IHC-P (1:50), WB (1:100 - 1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Section Bar
 Immunohistochemistry (IHC) of anti-CAT antibody    Anti-Catalase antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
anti-CAT antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Western Blot (WB) of anti-CAT antibody     
anti-CAT antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CAT. It may not necessarily be applicable to this product.
 NCBI GI #    4557014
 NCBI GeneID    847
 NCBI Accession #    NP_001743.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001752.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P04040 [Other Products]
 UniProt Secondary Accession #    Q2M1U4; Q4VXX5; Q9BWT9; Q9UC85; A8K6C0; B2RCZ9; D3DR07 [Other Products]
 UniProt Related Accession #    P04040 [Other Products]
 Molecular Weight    59,756 Da
Table BarTOPTable Bar
 NCBI Official Full Name    catalase
 NCBI Official Synonym Full Names    catalase
 NCBI Official Symbol    CAT [Similar Products]
 NCBI Protein Information    catalase
 UniProt Protein Name    Catalase
 UniProt Gene Name    CAT [Similar Products]
 UniProt Entry Name    CATA_HUMAN
Section Bar
 NCBI Summary for CAT    This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
Section Bar
 UniProt Comments for CAT    Catalase: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. Homotetramer. Belongs to the catalase family.

Protein type: Oxidoreductase; Apoptosis; Energy Metabolism - methane; EC 1.11.1.6; Mitochondrial; Amino Acid Metabolism - tryptophan; Hydrolase; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: peroxisomal membrane; Golgi apparatus; peroxisomal matrix; focal adhesion; intracellular membrane-bound organelle; membrane; endoplasmic reticulum; lysosome; plasma membrane; mitochondrial intermembrane space; peroxisome; cytosol

Molecular Function: antioxidant activity; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity; enzyme binding; catalase activity; metal ion binding; heme binding; NADP binding; aminoacylase activity; receptor binding

Biological Process: cholesterol metabolic process; nucleobase, nucleoside and nucleotide metabolic process; hemoglobin metabolic process; purine base metabolic process; protein homotetramerization; activation of NF-kappaB transcription factor; positive regulation of phosphoinositide 3-kinase cascade; osteoblast differentiation; response to vitamin E; response to reactive oxygen species; triacylglycerol metabolic process; response to hyperoxia; UV protection; hydrogen peroxide catabolic process; ureteric bud development; inhibition of NF-kappaB transcription factor; positive regulation of cell division; response to hypoxia; aerobic respiration; purine nucleotide catabolic process; protein tetramerization; negative regulation of apoptosis; aging

Disease: Acatalasemia
Table BarTOPTable Bar
 Research Articles on CAT    1. Serum catalase activity in patients with chronic tonsillitis was significantly higher than in healthy controls.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CAT antibodyPathways associated with anti-CAT antibody
 Reference Product  PubMed Publications
 SOD1 antibody  >193 publications with CAT and SOD1
 SOD2 antibody  >154 publications with CAT and SOD2
 GPX1 antibody  >140 publications with CAT and GPX1
 SOD3 antibody  >27 publications with CAT and SOD3
 GPX4 antibody  >24 publications with CAT and GPX4
 XDH antibody  >10 publications with CAT and XDH
 FOXO3 antibody  >7 publications with CAT and FOXO3
 GPX5 antibody  >5 publications with CAT and GPX5
 ALDH2 antibody  >5 publications with CAT and ALDH2
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
 FoxO Signaling Pathway antibodies  FoxO Signaling Pathway Diagram
 Glyoxylate And Dicarboxylate Metabolism Pathway antibodies  Glyoxylate And Dicarboxylate Metabolism Pathway Diagram
Diseases associated with anti-CAT antibodyOrgans/Tissues associated with anti-CAT antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1340 publications with CAT and Necrosis
 Asthma Antibodies  >1305 publications with CAT and Asthma
 Diabetes Mellitus Antibodies  >1188 publications with CAT and Diabetes Mellitus
 Hypertension Antibodies  >844 publications with CAT and Hypertension
 Edema Antibodies  >718 publications with CAT and Edema
 Seizures Antibodies  >682 publications with CAT and Seizures
 Disease Progression Antibodies  >586 publications with CAT and Disease Progression
 Brain Ischemia Antibodies  >561 publications with CAT and Brain Ischemia
 Heart Failure Antibodies  >480 publications with CAT and Heart Failure
 Reperfusion Injury Antibodies  >457 publications with CAT and Reperfusion Injury
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23248 publications with CAT and Brain
 Blood Antibodies  >16532 publications with CAT and Blood
 Nerve Antibodies  >10483 publications with CAT and Nerve
 Muscle Antibodies  >9693 publications with CAT and Muscle
 Eye Antibodies  >5889 publications with CAT and Eye
 Vascular Antibodies  >4948 publications with CAT and Vascular
 Heart Antibodies  >4842 publications with CAT and Heart
 Liver Antibodies  >4824 publications with CAT and Liver
 Skin Antibodies  >4298 publications with CAT and Skin
 Kidney Antibodies  >3303 publications with CAT and Kidney
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions