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anti-CD102 antibody :: Mouse CD102 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS215804
Unit / Price
0.025 mg  /  $165 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD102, Monoclonal Antibody

 Also Known As   

MOUSE ANTI HUMAN CD102:FITC

 Product Gene Name   

anti-CD102 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    146630
 3D Structure    ModBase 3D Structure for P13598
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 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    CBRIC2/2
 Host    Mouse
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 Form/Format    FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
 Concentration    IgG concentration 0.1 mg/ml (lot specific)
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 Perservative Stabilisers    0.09% Sodium Azide
1% Bovine Serum Albumin
Preparation
 Immunogen    Transfected COS cells expressing ICAM-2 cDNA
Fusion Partners
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD102 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CD102 antibody

   Mouse anti Human CD102 antibody, clone CBRIC2/2 recognizes human CD102, also known as intercellular adhesion molecule-2 (ICAM-2). CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD18 (LFA-1). Reports suggest that the CD102 may play a role in lymphocyte re-circulation and T-cell activation. Mouse anti Human CD102 antibody, clone CBRIC2/2 is reported to inhibit interactions between CD102 and LFA-1 (De Fougerolles et al. 1991).
 Applications Tested/Suitable for anti-CD102 antibody   

Flow cytometry (FC/FACS)

 Application Notes for anti-CD102 antibody    Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/10
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 Testing Data of anti-CD102 antibody    Staining of human peripheral blood lymphocytes with Mouse anti Human CD102 (MBS212661)
anti-CD102 antibody Testing Data image
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 Testing Data of anti-CD102 antibody    Stainig of human peripheral blood lymphocytes probed with Mouse anti Human CD102: Low Endotoxin (MBS211224)
anti-CD102 antibody Testing Data image
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 Testing Data of anti-CD102 antibody    Staining of human peripheral blood lymphocytes with Mouse anti Human CD102: Alexa Fluor 488 (MBS212661A488)
anti-CD102 antibody Testing Data image
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 Testing Data of anti-CD102 antibody    Staining of peripheral blood monocytes with Mouse anti Human CD102: Biotin (MBS210438)
anti-CD102 antibody Testing Data image
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 Testing Data of anti-CD102 antibody    Stainingof human peripheral blood lymphocytes with Mouse anti Human CD102: Alexa Fluor 647 (MBS212661A647)
anti-CD102 antibody Testing Data image
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 Testing Data of anti-CD102 antibody    Staining of human peripheral blood monocytes with Mouse anti Human CD102: FITC (MBS210922)
anti-CD102 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CD102. It may not necessarily be applicable to this product.
 NCBI GI #    153082696
 NCBI GeneID    3384
 NCBI Accession #    NP_000864.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000873.3 [Other Products]
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 UniProt Primary Accession #    P13598 [Other Products]
 UniProt Secondary Accession #    Q14600 [Other Products]
 UniProt Related Accession #    P13598 [Other Products]
 Molecular Weight    30,654 Da
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 NCBI Official Full Name    intercellular adhesion molecule 2
 NCBI Official Synonym Full Names    intercellular adhesion molecule 2
 NCBI Official Symbol    ICAM2 [Similar Products]
 NCBI Official Synonym Symbols   
CD102
[Similar Products]
 NCBI Protein Information    intercellular adhesion molecule 2; ICAM-2
 UniProt Protein Name    Intercellular adhesion molecule 2
 UniProt Synonym Protein Names   
CD_antigen: CD102
 UniProt Gene Name    ICAM2 [Similar Products]
 UniProt Synonym Gene Names    ICAM-2 [Similar Products]
 UniProt Entry Name    ICAM2_HUMAN
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 NCBI Summary for CD102    The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD102    ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: membrane; integral to plasma membrane; plasma membrane; uropod

Molecular Function: integrin binding

Biological Process: cell-cell adhesion; extracellular matrix organization and biogenesis; regulation of immune response; cell adhesion
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 Research Articles on CD102    1. with larger patient groups and preferably detailed histopathological and clinical evaluations, are needed to explain the severity of ICAM-1, ICAM-2, and ICAM-3 molecules in Barrett's esophagus
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD102 antibodyPathways associated with anti-CD102 antibody
 Reference Product  PubMed Publications
 ICAM1 antibody  >163 publications with CD102 and ICAM1
 ITGB2 antibody  >58 publications with CD102 and ITGB2
 ICAM3 antibody  >49 publications with CD102 and ICAM3
 ITGAL antibody  >42 publications with CD102 and ITGAL
 ITGAM antibody  >20 publications with CD102 and ITGAM
 CD209 antibody  >1 publications with CD102 and CD209
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Natural Killer Cell Mediated Cytotoxicity Pathway antibodies  Natural Killer Cell Mediated Cytotoxicity Pathway Diagram
 Amb2 Integrin Signaling Pathway antibodies  Amb2 Integrin Signaling Pathway Diagram
Diseases associated with anti-CD102 antibodyOrgans/Tissues associated with anti-CD102 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >39 publications with CD102 and Inflammation
 Necrosis Antibodies  >28 publications with CD102 and Necrosis
 Lung Diseases Antibodies  >8 publications with CD102 and Lung Diseases
 Liver Diseases Antibodies  >5 publications with CD102 and Liver Diseases
 Heart Diseases Antibodies  >5 publications with CD102 and Heart Diseases
 Pancreatic Diseases Antibodies  >3 publications with CD102 and Pancreatic Diseases
 Neoplasms, Experimental Antibodies  >3 publications with CD102 and Neoplasms, Experimental
 Myocardial Infarction Antibodies  >3 publications with CD102 and Myocardial Infarction
 Hemorrhage Antibodies  >3 publications with CD102 and Hemorrhage
 Kidney Diseases Antibodies  >2 publications with CD102 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >180 publications with CD102 and Blood
 Vascular Antibodies  >110 publications with CD102 and Vascular
 Lung Antibodies  >19 publications with CD102 and Lung
 Liver Antibodies  >18 publications with CD102 and Liver
 Brain Antibodies  >16 publications with CD102 and Brain
 Lymph Node Antibodies  >15 publications with CD102 and Lymph Node
 Lymph Antibodies  >14 publications with CD102 and Lymph
 Embryonic Tissue Antibodies  >12 publications with CD102 and Embryonic Tissue
 Heart Antibodies  >11 publications with CD102 and Heart
 Umbilical Cord Antibodies  >10 publications with CD102 and Umbilical Cord
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