Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CD106 rightarrow Monoclonal CD106  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • C Reactive Protein (CRP) ELISA Kit
 • Transferrin (TF) Native Protein
 • 5-hydroxytryptamine receptor 2A (HTR2A) Recombinant Protein
 • DUSP1 Antibody
 • Goat anti Guinea Pig IgM (Fc specific) Secondary Antibody
 • SPRED1 Antibody
 • Vacuolar protein sorting-associated protein 35 (VPS35) Recombinant Protein
 • Alkaline Phosphatase (ALP) Enzyme
 • gonadotropin-releasing hormone 1 (luteinizing-releasing horm... ELISA Kit
 • Gonadotropin Releasing Hormone (GnRH) ELISA Kit
 • Aromatase-CYP19A1 (CYP19A1 ) Antibody
 • Bu-1a Secondary Antibody
 • D-Dopachrome Tautomerase (DDT) ELISA Kit
 • Interferon alpha (IFN-alpha) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CD106 antibody :: Mouse CD106 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS219517
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD106, Monoclonal Antibody

 Also Known As   

MOUSE ANTI RAT CD106:FITC

 Product Gene Name   

anti-CD106 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 3D Structure    ModBase 3D Structure for P29534
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    MR106
 Host    Mouse
Section Bar
 Form/Format    FITC
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
 Concentration    IgG concentration 0.1mg/ml (lot specific)
Section Bar
 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Preparation
 Immunogen    Rat CD106-transfected L5178Y cells
Buffer Solution
 Target Species    Rat
Section Bar
 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD106 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-CD106 antibody

   Mouse anti Rat CD106 antibody, clone MR106 specifically recognizes rat CD106, otherwise known as VCAM-1 (vascular adhesion molecule 1), a 110kDa inducible type I transmembrane glycoprotein and member of the immunoglobulin supergene family, which is predominantly expressed on vascular endothelium, and also on bone marrow stromal cells, follicular dendritic cells and some macrophages. CD106 interacts with the lymphocyte homing receptor VLA-4 (alpha4 beta1 integrin) and LPAM-1 (alpha4 beta7 integrin) and mediates leucocyte-endothelial cell adhesion and signal transduction. Expression of CD106 is upregulated following cytokine activation, and endothelial CD106 plays a role in the extravasation of leucocytes from blood vessels during inflammation.
 Applications Tested/Suitable for anti-CD106 antibody   

Flow cytometry (FC/FACS)

 Application Notes for anti-CD106 antibody    Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/5
Section Bar
 Testing Data of anti-CD106 antibody    Staining of rat bone marrow cells with Mouse anti Rat CD106:RPE (MBS219407)
anti-CD106 antibody Testing Data image
Section Bar
 Testing Data of anti-CD106 antibody    Staining of rat bone marrow cells with Mouse anti Rat CD106:FITC
anti-CD106 antibody Testing Data image
Section Bar
 Testing Data of anti-CD106 antibody    Staining of rat bone marrow cells with Mouse anti Rat CD106:Alexa Fluor 647 (MBS219615A647)
anti-CD106 antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD106. It may not necessarily be applicable to this product.
 NCBI GI #    6981700
 NCBI GeneID    25361
 NCBI Accession #    NP_037021.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012889.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P29534 [Other Products]
 UniProt Secondary Accession #    Q5FVS3; Q63669 [Other Products]
 UniProt Related Accession #    P29534 [Other Products]
 Molecular Weight    81,246 Da
Table BarTOPTable Bar
 NCBI Official Full Name    vascular cell adhesion protein 1
 NCBI Official Synonym Full Names    vascular cell adhesion molecule 1
 NCBI Official Symbol    Vcam1 [Similar Products]
 NCBI Official Synonym Symbols   
VCAM1B
[Similar Products]
 NCBI Protein Information    vascular cell adhesion protein 1; V-CAM 1; VCAM-1
 UniProt Protein Name    Vascular cell adhesion protein 1
 UniProt Synonym Protein Names   
CD_antigen: CD106
 UniProt Gene Name    Vcam1 [Similar Products]
 UniProt Synonym Gene Names    Vcam-1; V-CAM 1; VCAM-1 [Similar Products]
 UniProt Entry Name    VCAM1_RAT
Section Bar
 NCBI Summary for CD106    binds integrin very late antigen (VLA4); plays a role in cell adhesion [RGD, Feb 2006]
Section Bar
 UniProt Comments for CD106    VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, integral

Cellular Component: Golgi apparatus; extracellular space; microvillus; cell surface; endoplasmic reticulum; apical part of cell; early endosome; integral to membrane; podosome; sarcolemma; filopodium; external side of plasma membrane

Molecular Function: amine oxidase activity; integrin binding; cell adhesion molecule binding

Biological Process: response to nicotine; chronic inflammatory response; viral reproduction; heart development; cell-matrix adhesion; response to lipopolysaccharide; heterophilic cell adhesion; leukocyte adhesion; response to ethanol; response to zinc ion; membrane to membrane docking; response to hypoxia; positive regulation of T cell proliferation; response to ionizing radiation; amine metabolic process; cell adhesion; leukocyte tethering or rolling; response to nutrient; acute inflammatory response; aging
Table BarTOPTable Bar
 Research Articles on CD106    1. Upregulation of the adhesion molecules VCAM-1, ICAM-1, and E-selectin.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-CD106 antibodyDiseases associated with anti-CD106 antibody
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >86 publications with CD106 and Inflammation
 Cardiovascular Diseases Antibodies  >54 publications with CD106 and Cardiovascular Diseases
 Necrosis Antibodies  >50 publications with CD106 and Necrosis
 Atherosclerosis Antibodies  >42 publications with CD106 and Atherosclerosis
 Kidney Diseases Antibodies  >13 publications with CD106 and Kidney Diseases
 Hypertension Antibodies  >12 publications with CD106 and Hypertension
 Heart Diseases Antibodies  >11 publications with CD106 and Heart Diseases
 Myocardial Ischemia Antibodies  >9 publications with CD106 and Myocardial Ischemia
 Anemia Antibodies  >8 publications with CD106 and Anemia
 Myocardial Infarction Antibodies  >7 publications with CD106 and Myocardial Infarction
Organs/Tissues associated with anti-CD106 antibody
 Organ/Tissue Name  Pubmed Publications
 Artery Antibodies  >31 publications with CD106 and Artery
 Kidney Antibodies  >24 publications with CD106 and Kidney
 Embryonic Tissue Antibodies  >22 publications with CD106 and Embryonic Tissue
 Brain Antibodies  >20 publications with CD106 and Brain
 Lung Antibodies  >13 publications with CD106 and Lung
 Spleen Antibodies  >6 publications with CD106 and Spleen
 Adipose Tissue Antibodies  >6 publications with CD106 and Adipose Tissue
 Eye Antibodies  >3 publications with CD106 and Eye
 Pancreas Antibodies  >3 publications with CD106 and Pancreas
 Prostate Antibodies  >2 publications with CD106 and Prostate
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions