Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CD11b rightarrow Monoclonal CD11b  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • SERC3 Antibody
 • Soluble Cluster of Differentiation 30 Ligand (SCD30L) ELISA Kit
 • Toll Like Receptor4 (TLR4) ELISA Kit
 • beta2-Glycoprotein 1 Antibody IgM (beta2-GP1 AB IgM) ELISA Kit
 • Corticotropin Releasing Hormone Receptor (CRH-R) ELISA Kit
 • Gastrin (GT) ELISA Kit
 • C-Myc Oncogene Product ELISA Kit
 • Insulin ELISA Kit
 • Pulmonary Surfactant Associated Protein B (SPB) ELISA Kit
 • Cyclin Dependent Kinase 2 (CDK-2) ELISA Kit
 • Choline Acetyltransferase (CHAT) ELISA Kit
 • Cyclin D (CD) ELISA Kit
 • Klotho Beta (KLbeta) ELISA Kit
 • Alpha-1-Antichymotrypsin (alpha1ACT) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CD11b antibody :: Rat CD11b Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS216561
Unit / Price
0.025 mg  /  $155 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD11b, Monoclonal Antibody

 Also Known As   

RAT ANTI MOUSE CD11b:Biotin

 Product Gene Name   

anti-CD11b antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    M1/70.15
 Host    Rat
Section Bar
 Form/Format    Biotin
Purified IgG conjugated to Biotin - liquid
 Concentration    IgG concentration 0.1 mg/ml (lot specific)
Section Bar
 Perservative Stabilisers    0.09% Sodium Azide
1% Bovine Serum Albumin
Preparation
 Immunogen    T cell enriched splenocytes from B10 mice
Fusion Partners
 Target Species    Mouse
Section Bar
 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-CD11b antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-CD11b antibody   

Flow cytometry (FC/FACS)

 Application Notes for anti-CD11b antibody    Flow Cytometry: Maximum Dilution: Neat
Section Bar
 Testing Data of anti-CD11b antibody    Immunoperoxidase staining of mouse lymph node cryosection using Rat anti Mouse CD11b antibody followed by horseradish peroxidase conjugated Goat anti Rat IgG (MBS235195). Medium power
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b: Alexa Fluor 647
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Immunoperoxidase staining of mouse lymph node cryosection using Rat anti Mouse CD11b antibody followed by horseradish peroxidase conjugated Goat anti Rat IgG (MBS235195). High power
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Staining of mouse peritoneal macrophages cells with Rat anti Mouse CD11b:FITC (MBS211086)
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b:RPE (MBS213875)
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Published customer image: Immunocytochemical characterisation of cultures of mouse microglia. Cultures of microglia were immunostained with anti-CD11b (a) and anti-GFAP (c). Cultures of astrocytes were immunostained with anti-CD11b (c) and anti-GFAP (d). All cells were also counterstained with DAPI (blue) to identify the cells' nuclei.From: Ferger et al. Journal of Neuroinflammation 2010 7:45
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Staining of total mouse peritoneal exudate cells demonstrating labelling of macrophages with Rat anti Mouse CD11b:RPE (MBS213874)
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Staining of mouse peritoneal macrophages cells with Rat anti Mouse CD11b:Alexa Fluor 488
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b (MBS213144)
anti-CD11b antibody Testing Data image
Section Bar
 Testing Data of anti-CD11b antibody    Staining of mouse peritoneal macrophages with Rat anti Mouse CD11b (MBS213143)
anti-CD11b antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CD11b. It may not necessarily be applicable to this product.
 NCBI GI #    124956
 NCBI GeneID    16409
 NCBI Accession #    P05555.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q8CA73 [Other Products]
 UniProt Related Accession #    P05555 [Other Products]
 Molecular Weight    115,196 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Integrin alpha-M
 NCBI Official Synonym Full Names    integrin alpha M
 NCBI Official Symbol    Itgam [Similar Products]
 NCBI Official Synonym Symbols   
CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik
[Similar Products]
 NCBI Protein Information    integrin alpha-M; CD11 antigen-like family member B; CD11B (p170); CR-3 alpha chain; Mac-1 alpha; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; leukocyte adhesion receptor MO1; macrophage antigen alpha
 UniProt Protein Name    Integrin alpha-M
 UniProt Synonym Protein Names   
CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; CD_antigen: CD11b
 UniProt Gene Name    Itgam [Similar Products]
 UniProt Entry Name    ITAM_MOUSE
Section Bar
 UniProt Comments for CD11b    ITGAM: a single-pass type I membrane protein of the integrin alpha chain family. Implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Also known as CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. A receptor for fibrinogen, factor X and ICAM1. Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2. Predominantly expressed in monocytes and granulocytes.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Cellular Component: cell surface; membrane; integral to membrane; nucleus; integrin complex; external side of plasma membrane

Molecular Function: heparin binding; heparan sulfate proteoglycan binding; opsonin binding; protein heterodimerization activity; metal ion binding; glycoprotein binding

Biological Process: integrin-mediated signaling pathway; neutrophil chemotaxis; cell-cell adhesion; leukocyte adhesion; microglia development; cellular extravasation; activated T cell proliferation; cell adhesion; leukocyte migration during inflammatory response
Table BarTOPTable Bar
 Research Articles on CD11b    1. These findings indicate that inhibition of indoleamine 2,3-dioxygenase-1 reduces mortality from peritonitis and sepsis after CLP via recruitment of neutrophils and mononuclear cells by chemokine production in peritoneal CD11b(+) cells.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with anti-CD11b antibodyOrgans/Tissues associated with anti-CD11b antibody
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4528 publications with CD11b and Blood
 Bone Marrow Antibodies  >798 publications with CD11b and Bone Marrow
 Brain Antibodies  >631 publications with CD11b and Brain
 Lung Antibodies  >545 publications with CD11b and Lung
 Spleen Antibodies  >519 publications with CD11b and Spleen
 Skin Antibodies  >248 publications with CD11b and Skin
 Heart Antibodies  >211 publications with CD11b and Heart
 Spinal Cord Antibodies  >164 publications with CD11b and Spinal Cord
 Intestine Antibodies  >161 publications with CD11b and Intestine
 Eye Antibodies  >152 publications with CD11b and Eye
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions