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anti-cd123 antibody :: Rat anti-Mouse CD123 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS601234 anti-cd123 antibody
Unit / Price
0.25 mg  /  $545 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD123, Monoclonal Antibody

 Also Known As   

CD123 (IL-3 Receptor alpha, IL-3Ra)

 Product Synonym Names    Anti -CD123 (IL-3 Receptor alpha, IL-3Ra)
 Product Gene Name   

anti-cd123 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Monoclonal
 Isotype    IgG2a
 Clone Number    6A367
 Host    Rat
 Species Reactivity    Mouse
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 Specificity    Recognizes murine CD123, which is the 70kD alpha chain of the interleukin-3 receptor (IL-3R). Does not block the binding of IL-3 to the high affinity IL-3 receptor.
 Purity/Purification    Affinity Purified
Purified by Protein G affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
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 Immunogen    CTLL cells transfected with mouse CD123.
 Recommended Negative Controls    I1904-82D1: IgG2a, Rat Negative Control
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-cd123 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-cd123 antibody

   CD123 is expressed on hematopoietic progenitors and most myeloid cells including basophils and mast cells. Certain mouse strains including A/J, AKR/J and NZB/B1NJ are reported to have low levels of CD123 expression due to aberrant splicing of the IL-3R alpha subunit gene. In mouse, CD123 can associate with either the common beta subunit CDw131 or with the murine IL-3 beta subunit to form a high affinity receptor for IL-3. IL-3 can bind to CD123 itself but with low affinity. Binding of IL-3 to the IL-3 receptor complex induces the proliferation and differentiation of hematopoietic cells.
 Product Categories/Family for anti-cd123 antibody    Antibodies; Abs to CD Markers
 Applications Tested/Suitable for anti-cd123 antibody   

Flow Cytometry (FC/FACS)

 Application Notes for anti-cd123 antibody    Suitable for use in Flow Cytometry.
Dilution: Flow Cytometry: 1:10-1:50. Use 10ul to label 10e6 cells in 100ul.
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NCBI/Uniprot data below describe general gene information for cd123. It may not necessarily be applicable to this product.
 NCBI GI #    318067902
 NCBI GeneID    100528235
 NCBI Accession #    NP_001187434.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001200505.1 [Other Products]
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 NCBI Official Full Name    cell division cycle protein 123-like protein
 NCBI Official Symbol    cd123 [Similar Products]
 NCBI Protein Information    cell division cycle protein 123-like protein
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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